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Term Detail
GO term:reactive oxygen species metabolic process
Synonym: reactive oxygen species metabolism
Synonym: ROS metabolic process
GO id:GO:0072593
Definition:The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aauxin metabolic process +
                                is-abioluminescence
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkene metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular aromatic compound metabolic process +
                                is-acellular biosynthetic process +
                                is-acellular carbohydrate metabolic process +
                                is-acellular catabolic process +
                                is-acellular hormone metabolic process +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular macromolecule metabolic process +
                                is-acellular modified amino acid metabolic process +
                                is-acellular nitrogen compound metabolic process +
                                is-acellular organohalogen metabolic process +
                                is-acofactor metabolic process +
                                is-adrug metabolic process +
                                is-ageneration of precursor metabolites and energy +
                                is-aheterocycle metabolic process +
                                is-ahydroperoxide metabolic process
                                is-amucilage metabolic process +
                                negatively-regulatesnegative regulation of cellular metabolic process +
                                is-aneurotransmitter metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorganometal metabolic process +
                                is-aoxygen metabolic process +
                                is-apheromone metabolic process +
                                is-aphosphorus metabolic process +
                                is-aphotosynthesis +
                                positively-regulatespositive regulation of cellular metabolic process +
                                is-aprenylation +
                                is-areactive oxygen species metabolic process [GO:0072593] (217 genes, 332 annotations)
                                        is-ahydrogen peroxide metabolic process +
                                        is-ahypochlorous acid metabolic process +
                                        negatively-regulatesnegative regulation of reactive oxygen species metabolic process +
                                        is-anitric oxide metabolic process +
                                        positively-regulatespositive regulation of reactive oxygen species metabolic process +
                                        is-areactive oxygen species biosynthetic process +
                                        regulatesregulation of reactive oxygen species metabolic process +
                                        regulatesregulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter
                                        regulatesregulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter
                                        is-asuperoxide metabolic process +
                                regulatesregulation of cellular metabolic process +
                                is-aselenium compound metabolic process +
                                is-asulfur compound metabolic process +
                                is-atoxin metabolic process +
                                is-atranslational initiation +
                                is-axenobiotic metabolic process +


obsolete Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aauxin metabolic process +
                                is-abioluminescence
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkene metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular aromatic compound metabolic process +
                                is-acellular biosynthetic process +
                                is-acellular carbohydrate metabolic process +
                                is-acellular catabolic process +
                                is-acellular hormone metabolic process +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular macromolecule metabolic process +
                                is-acellular modified amino acid metabolic process +
                                is-acellular nitrogen compound metabolic process +
                                is-acellular organohalogen metabolic process +
                                is-acofactor metabolic process +
                                is-adrug metabolic process +
                                is-ageneration of precursor metabolites and energy +
                                is-aheterocycle metabolic process +
                                is-ahydroperoxide metabolic process
                                is-amucilage metabolic process +
                                negatively-regulatesnegative regulation of cellular metabolic process +
                                is-aneurotransmitter metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorganometal metabolic process +
                                is-aoxygen metabolic process +
                                is-apheromone metabolic process +
                                is-aphosphorus metabolic process +
                                is-aphotosynthesis +
                                positively-regulatespositive regulation of cellular metabolic process +
                                is-aprenylation +
                                is-areactive oxygen species metabolic process [GO:0072593] (217 genes, 332 annotations)
                                        is-ahydrogen peroxide metabolic process +
                                        is-ahypochlorous acid metabolic process +
                                        negatively-regulatesnegative regulation of reactive oxygen species metabolic process +
                                        is-anitric oxide metabolic process +
                                        positively-regulatespositive regulation of reactive oxygen species metabolic process +
                                        is-areactive oxygen species biosynthetic process +
                                        regulatesregulation of reactive oxygen species metabolic process +
                                        regulatesregulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter
                                        regulatesregulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter
                                        is-asuperoxide metabolic process +
                                regulatesregulation of cellular metabolic process +
                                is-aselenium compound metabolic process +
                                is-asulfur compound metabolic process +
                                is-atoxin metabolic process +
                                is-atranslational initiation +
                                is-axenobiotic metabolic process +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory