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Term Detail
GO term:reactive oxygen species metabolic process
Synonym: reactive oxygen species metabolism
Synonym: ROS metabolic process
GO id:GO:0072593
Definition:The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aauxin metabolic process +
                                is-abioluminescence
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkene metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular aromatic compound metabolic process +
                                is-acellular biosynthetic process +
                                is-acellular carbohydrate metabolic process +
                                is-acellular catabolic process +
                                is-acellular hormone metabolic process +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular macromolecule metabolic process +
                                is-acellular nitrogen compound metabolic process +
                                is-acellular organohalogen metabolic process +
                                is-acofactor metabolic process +
                                is-adrug metabolic process +
                                is-ageneration of precursor metabolites and energy +
                                is-aheterocycle metabolic process +
                                is-ahydroperoxide metabolic process
                                is-amucilage metabolic process +
                                negatively-regulatesnegative regulation of cellular metabolic process +
                                is-aneurotransmitter metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorganometal metabolic process +
                                is-aoxygen metabolic process +
                                is-apheromone metabolic process +
                                is-aphosphorus metabolic process +
                                is-aphotosynthesis +
                                positively-regulatespositive regulation of cellular metabolic process +
                                is-aprenylation +
                                is-areactive oxygen species metabolic process [GO:0072593] (148 genes, 228 annotations)
                                        is-ahydrogen peroxide metabolic process +
                                        is-ahypochlorous acid metabolic process +
                                        negatively-regulatesnegative regulation of reactive oxygen species metabolic process +
                                        positively-regulatespositive regulation of reactive oxygen species metabolic process +
                                        is-areactive oxygen species biosynthetic process +
                                        regulatesregulation of reactive oxygen species metabolic process +
                                        is-asuperoxide metabolic process +
                                regulatesregulation of cellular metabolic process +
                                is-aselenium compound metabolic process +
                                is-asulfur compound metabolic process +
                                is-athioester metabolic process +
                                is-atoxin metabolic process +
                                is-atranslational initiation +
                                is-axenobiotic metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aauxin metabolic process +
                                is-abioluminescence
                                is-acellular alcohol metabolic process +
                                is-acellular aldehyde metabolic process +
                                is-acellular alkane metabolic process +
                                is-acellular alkene metabolic process +
                                is-acellular alkyne metabolic process +
                                is-acellular aromatic compound metabolic process +
                                is-acellular biosynthetic process +
                                is-acellular carbohydrate metabolic process +
                                is-acellular catabolic process +
                                is-acellular hormone metabolic process +
                                is-acellular ketone body metabolic process +
                                is-acellular ketone metabolic process +
                                is-acellular lipid metabolic process +
                                is-acellular macromolecule metabolic process +
                                is-acellular nitrogen compound metabolic process +
                                is-acellular organohalogen metabolic process +
                                is-acofactor metabolic process +
                                is-adrug metabolic process +
                                is-ageneration of precursor metabolites and energy +
                                is-aheterocycle metabolic process +
                                is-ahydroperoxide metabolic process
                                is-amucilage metabolic process +
                                negatively-regulatesnegative regulation of cellular metabolic process +
                                is-aneurotransmitter metabolic process +
                                is-aone-carbon metabolic process +
                                is-aorganic acid metabolic process +
                                is-aorganometal metabolic process +
                                is-aoxygen metabolic process +
                                is-apheromone metabolic process +
                                is-aphosphorus metabolic process +
                                is-aphotosynthesis +
                                positively-regulatespositive regulation of cellular metabolic process +
                                is-aprenylation +
                                is-areactive oxygen species metabolic process [GO:0072593] (148 genes, 228 annotations)
                                        is-ahydrogen peroxide metabolic process +
                                        is-ahypochlorous acid metabolic process +
                                        negatively-regulatesnegative regulation of reactive oxygen species metabolic process +
                                        positively-regulatespositive regulation of reactive oxygen species metabolic process +
                                        is-areactive oxygen species biosynthetic process +
                                        regulatesregulation of reactive oxygen species metabolic process +
                                        is-asuperoxide metabolic process +
                                regulatesregulation of cellular metabolic process +
                                is-aselenium compound metabolic process +
                                is-asulfur compound metabolic process +
                                is-athioester metabolic process +
                                is-atoxin metabolic process +
                                is-atranslational initiation +
                                is-axenobiotic metabolic process +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory