Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RDH16
  • Mouse genes Rdh16
  • Rat genes Rdh16
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rdh16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	RDH16	IDA		Human	PMID:10329026
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	RDH16	IDA		Human	PMID:9677409
Molecular Function	GO:0047023	androsterone dehydrogenase activity	RDH16	IDA		Human	PMID:9677409
Molecular Function	GO:0042802	identical protein binding	Rdh16	IDA		Mouse	MGI:MGI:3611991|PMID:16223484
Molecular Function	GO:0042802	identical protein binding	Rdh16	IPI	PR:O54909	Mouse	PMID:16223484
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	RDH16	IDA		Human	PMID:10329026
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	RDH16	IDA		Human	PMID:12534290
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	RDH16	IDA		Human	PMID:9677409
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	Rdh16	IDA		Mouse	MGI:MGI:1101408|PMID:9407098
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	Rdh16	IDA		Mouse	PMID:11876656
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	Rdh16	IDA		Mouse	PMID:16223484
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	Rdh16	IDA		Rat	PMID:7499345|RGD:1299624
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Rdh16	IDA		Mouse	PMID:16223484
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Rdh16	IDA		Mouse	MGI:MGI:6282955|PMID:15355969
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Rdh16	IDA		Rat	PMID:11601977|RGD:14390050
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RDH16	IDA		Human	PMID:9677409
Cellular Component	GO:0031090	organelle membrane	Rdh16	IDA		Mouse	PMID:16223484
Cellular Component	GO:0031090	organelle membrane	Rdh16	IDA		Rat	PMID:11601977|RGD:14390050
Biological Process	GO:0042904	9-cis-retinoic acid biosynthetic process	Rdh16	IDA		Mouse	PMID:11876656
Biological Process	GO:1900054	positive regulation of retinoic acid biosynthetic process	Rdh16	IMP		Rat	PMID:21138835|RGD:6771354
Biological Process	GO:0042573	retinoic acid metabolic process	Rdh16	IDA		Rat	PMID:7499345|RGD:1299624
Biological Process	GO:0001523	retinoid metabolic process	Rdh16	IDA		Mouse	MGI:MGI:1101408|PMID:9407098
Biological Process	GO:0042572	retinol metabolic process	Rdh16	IDA		Rat	PMID:7499345|RGD:1299624
Biological Process	GO:0008202	steroid metabolic process	RDH16	IDA		Human	PMID:9677409
Biological Process	GO:0008202	steroid metabolic process	Rdh16	IDA		Mouse	MGI:MGI:1101408|PMID:9407098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern