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Term Detail
GO term:retinol dehydrogenase activity
Synonym: all-trans retinol dehydrogenase activity
Synonym: MDR
Synonym: microsomal retinol dehydrogenase activity
Synonym: retinal reductase activity
Synonym: retinene reductase activity
Synonym: retinol:NAD+ oxidoreductase activity
Synonym: retinol (vitamin A1) dehydrogenase activity
GO id:GO:0004745
Definition:Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-aoxidoreductase activity, acting on CH-OH group of donors
                                        is-aoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
                                                is-a(+)-borneol dehydrogenase activity
                                                is-a(+)-neomenthol dehydrogenase activity
                                                is-a(+)-sabinol dehydrogenase activity
                                                is-a(+)-trans-carveol dehydrogenase activity
                                                is-a(-)-borneol dehydrogenase activity
                                                is-a(-)-menthol dehydrogenase activity
                                                is-a(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
                                                is-a(R)-2-hydroxy-fatty acid dehydrogenase activity
                                                is-a(R)-2-hydroxyacid dehydrogenase activity
                                                is-a(R)-2-hydroxyisocaproate dehydrogenase activity
                                                is-a(R)-3-hydroxyacid-ester dehydrogenase activity
                                                is-a(R)-4-hydroxyphenyllactate dehydrogenase activity
                                                is-a(R)-aminopropanol dehydrogenase activity
                                                is-a(R,R)-butanediol dehydrogenase activity
                                                is-a(S)-2-hydroxy-fatty acid dehydrogenase activity
                                                is-a(S)-3-hydroxyacid-ester dehydrogenase activity
                                                is-a(S)-carnitine 3-dehydrogenase activity
                                                is-a(S)-usnate reductase activity
                                                is-a(S,S)-butanediol dehydrogenase activity
                                                is-a1,3-propanediol dehydrogenase activity
                                                is-a1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity
                                                is-a1,5-anhydro-D-fructose reductase activity
                                                is-a1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
                                                is-a13-lipoxin reductase activity
                                                is-a13-prostaglandin reductase activity
                                                is-a15-hydroxyicosatetraenoate dehydrogenase activity
                                                is-a15-hydroxyprostaglandin dehydrogenase (NAD+) activity
                                                is-a15-hydroxyprostaglandin dehydrogenase (NADP+) activity
                                                is-a15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
                                                is-a15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity
                                                is-a2,5-didehydrogluconate reductase activity
                                                is-a2-(R)-hydroxypropyl-CoM dehydrogenase activity
                                                is-a2-(S)-hydroxypropyl-CoM dehydrogenase activity
                                                is-a2-alkyn-1-ol dehydrogenase activity
                                                is-a2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity
                                                is-a2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity
                                                is-a2-dehydropantoate 2-reductase activity
                                                is-a2-dehydropantolactone reductase activity +
                                                is-a2-deoxy-D-gluconate 3-dehydrogenase activity
                                                is-a2-hydroxy-3-oxopropionate reductase activity
                                                is-a2-hydroxymethylglutarate dehydrogenase activity
                                                is-a2-hydroxytetrahydrofuran dehydrogenase activity
                                                is-a2-oxoadipate reductase activity
                                                is-a3''-deamino-3''-oxonicotianamine reductase activity
                                                is-a3-(imidazol-5-yl)lactate dehydrogenase activity
                                                is-a3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity
                                                is-a3-alpha-hydroxycholanate dehydrogenase activity
                                                is-a3-alpha-hydroxyglycyrrhetinate dehydrogenase activity
                                                is-a3-dehydro-L-gulonate 2-dehydrogenase activity
                                                is-a3-dehydrosphinganine reductase activity
                                                is-a3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
                                                is-a3-hydroxyacyl-CoA dehydrogenase activity +
                                                is-a3-hydroxybenzyl-alcohol dehydrogenase activity
                                                is-a3-hydroxybutyrate dehydrogenase activity
                                                is-a3-hydroxybutyryl-CoA dehydrogenase activity
                                                is-a3-hydroxyisobutyrate dehydrogenase activity
                                                is-a3-hydroxymenthone dehydrogenase activity
                                                is-a3-hydroxypimeloyl-CoA dehydrogenase activity
                                                is-a3-hydroxypropionate dehydrogenase (NAD+) activity
                                                is-a3-hydroxypropionate dehydrogenase (NADP+) activity
                                                is-a3-isopropylmalate dehydrogenase activity
                                                is-a3-keto sterol reductase activity
                                                is-a3-ketoglucose-reductase activity
                                                is-a3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
                                                is-a3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
                                                is-a3-sulfolactaldehyde reductase activity
                                                is-a3beta-hydroxy-5alpha-steroid dehydrogenase activity
                                                is-a3beta-hydroxy-5beta-steroid dehydrogenase activity
                                                is-a4-(hydroxymethyl)benzenesulfonate dehydrogenase activity
                                                is-a4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity
                                                is-a4-hydroxybutyrate dehydrogenase activity
                                                is-a4-hydroxycyclohexanecarboxylate dehydrogenase activity
                                                is-a4-hydroxythreonine-4-phosphate dehydrogenase activity
                                                is-a4-oxoproline reductase activity
                                                is-a4-phosphoerythronate dehydrogenase activity
                                                is-a5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity
                                                is-a5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                                                is-a5-exo-hydroxycamphor dehydrogenase activity
                                                is-a5-hydroxyvalerate dehydrogenase activity
                                                is-a6-endo-hydroxycineole dehydrogenase activity
                                                is-a6-hydroxyhexanoate dehydrogenase activity
                                                is-a6-pyruvoyltetrahydropterin 2'-reductase activity
                                                is-a8-oxocoformycin reductase activity
                                                is-aacetoacetyl-CoA reductase activity
                                                is-aacetoin dehydrogenase activity +
                                                is-aacylglycerone-phosphate reductase activity
                                                is-aalcohol dehydrogenase (NAD) activity +
                                                is-aalcohol dehydrogenase [NAD(P)+] activity +
                                                is-aaldo-keto reductase (NADP) activity +
                                                is-aaldose 1-dehydrogenase activity
                                                is-aaldose-6-phosphate reductase (NADPH) activity
                                                is-aallyl-alcohol dehydrogenase activity
                                                is-aapiose 1-reductase activity
                                                is-aaryl-alcohol dehydrogenase (NAD+) activity
                                                is-aaryl-alcohol dehydrogenase (NADP+) activity
                                                is-abenzyl-2-methyl-hydroxybutyrate dehydrogenase activity
                                                is-aC-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
                                                is-acarbonyl reductase (NADPH) activity
                                                is-acarnitine 3-dehydrogenase activity
                                                is-acarveol dehydrogenase activity
                                                is-achlordecone reductase activity
                                                is-achlorophyll(ide) b reductase activity
                                                is-acholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
                                                is-acholestanetetraol 26-dehydrogenase activity
                                                is-acinnamyl-alcohol dehydrogenase activity
                                                is-acodeinone reductase (NADPH) activity
                                                is-aconiferyl-alcohol dehydrogenase activity
                                                is-acyclohexane-1,2-diol dehydrogenase activity
                                                is-acyclohexanol dehydrogenase activity
                                                is-acyclopentanol dehydrogenase activity
                                                is-aD-arabinitol 2-dehydrogenase activity
                                                is-aD-arabinitol 4-dehydrogenase activity
                                                is-aD-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity
                                                is-aD-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity
                                                is-aD-arabinose 1-dehydrogenase (NAD) activity
                                                is-aD-arabinose 1-dehydrogenase [NAD(P)+] activity
                                                is-aD-iditol 2-dehydrogenase activity
                                                is-aD-lactate dehydrogenase activity
                                                is-aD-malate dehydrogenase (decarboxylating) activity
                                                is-aD-pinitol dehydrogenase activity
                                                is-aD-threo-aldose 1-dehydrogenase activity
                                                is-aD-xylose 1-dehydrogenase (NAD) activity
                                                is-aD-xylose 1-dehydrogenase (NADP+) activity
                                                is-aD-xylulose reductase activity
                                                is-adiethyl 2-methyl-3-oxosuccinate reductase activity
                                                is-adihydrobunolol dehydrogenase activity
                                                is-adihydrokaempferol 4-reductase activity
                                                is-adiiodophenylpyruvate reductase activity
                                                is-adimethylmalate dehydrogenase activity
                                                is-adTDP-4-dehydro-6-deoxyglucose reductase activity
                                                is-adTDP-4-dehydrorhamnose reductase activity
                                                is-adTDP-6-deoxy-L-talose 4-dehydrogenase activity
                                                is-adTDP-galactose 6-dehydrogenase activity
                                                is-aepoxide dehydrogenase activity
                                                is-aerythrulose reductase activity
                                                is-afarnesol dehydrogenase activity
                                                is-aflavanone 4-reductase activity
                                                is-afluoren-9-ol dehydrogenase activity
                                                is-afructose 5-dehydrogenase (NADP+) activity
                                                is-afructuronate reductase activity
                                                is-agalactitol 2-dehydrogenase activity
                                                is-agalactitol-1-phosphate 5-dehydrogenase activity
                                                is-agalactose 1-dehydrogenase (NADP+) activity
                                                is-agalactose 1-dehydrogenase activity
                                                is-aGDP-4-dehydro-6-deoxy-D-mannose reductase activity
                                                is-aGDP-4-dehydro-D-rhamnose reductase activity
                                                is-aGDP-6-deoxy-D-talose 4-dehydrogenase activity
                                                is-aGDP-L-fucose synthase activity
                                                is-aGDP-mannose 6-dehydrogenase activity
                                                is-ageraniol dehydrogenase activity
                                                is-agluconate dehydrogenase activity +
                                                is-aglucose 1-dehydrogenase (NAD+) activity
                                                is-aglucose 1-dehydrogenase (NADP+) activity
                                                is-aglucose 1-dehydrogenase [NAD(P)] activity
                                                is-aglucose-6-phosphate dehydrogenase activity
                                                is-aglucuronolactone reductase activity
                                                is-aglycerate dehydrogenase activity
                                                is-aglycerol 2-dehydrogenase (NADP+) activity
                                                is-aglycerol dehydrogenase [NAD(P)+] activity
                                                is-aglycerol dehydrogenase [NAD+] activity
                                                is-aglycerol dehydrogenase [NADP+] activity
                                                is-aglycerol-1-phosphate dehydrogenase [NAD(P)+] activity
                                                is-aglycerol-3-phosphate 1-dehydrogenase [NADP+] activity
                                                is-aglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
                                                is-aglycerol-3-phosphate dehydrogenase [NAD+] activity
                                                is-aglycerol-3-phosphate dehydrogenase [NADP+] activity
                                                is-aglyoxylate reductase (NADP) activity
                                                is-aglyoxylate reductase activity
                                                is-ahexadecanol dehydrogenase activity
                                                is-ahistidinol dehydrogenase activity
                                                is-ahomoisocitrate dehydrogenase activity
                                                is-ahomoserine dehydrogenase activity
                                                is-ahydroxycyclohexanecarboxylate dehydrogenase activity
                                                is-ahydroxymalonate dehydrogenase activity
                                                is-ahydroxymethylfurfural reductase (NADH) activity
                                                is-ahydroxymethylfurfural reductase (NADPH) activity
                                                is-ahydroxymethylfurfural reductase activity
                                                is-ahydroxymethylglutaryl-CoA reductase (NADPH) activity
                                                is-ahydroxymethylglutaryl-CoA reductase activity
                                                is-ahydroxyphenylpyruvate reductase activity
                                                is-ahydroxypyruvate reductase activity
                                                is-aIMP dehydrogenase activity
                                                is-aindanol dehydrogenase activity
                                                is-aindole-3-acetaldehyde reductase (NADH) activity
                                                is-aindole-3-acetaldehyde reductase (NADPH) activity
                                                is-aindolelactate dehydrogenase activity
                                                is-aisocitrate dehydrogenase activity +
                                                is-aisocitrate-homoisocitrate dehydrogenase activity
                                                is-aisopiperitenol dehydrogenase activity
                                                is-aisopropanol dehydrogenase (NADP+) activity
                                                is-aketol-acid reductoisomerase activity
                                                is-aL-arabinitol 2-dehydrogenase activity
                                                is-aL-arabinitol 4-dehydrogenase activity
                                                is-aL-arabinose 1-dehydrogenase (NAD+) activity
                                                is-aL-arabinose 1-dehydrogenase (NADP+) activity
                                                is-aL-glucuronate reductase activity
                                                is-aL-glycol dehydrogenase activity
                                                is-aL-gulonate 3-dehydrogenase activity
                                                is-aL-iditol 2-dehydrogenase activity
                                                is-aL-idonate 5-dehydrogenase activity
                                                is-aL-lactate dehydrogenase activity
                                                is-aL-malate dehydrogenase activity
                                                is-aL-rhamnose 1-dehydrogenase activity
                                                is-aL-threonate 3-dehydrogenase activity
                                                is-aL-threonine 3-dehydrogenase activity
                                                is-aL-xylose 1-dehydrogenase activity
                                                is-aL-xylulose reductase (NAD+) activity
                                                is-aL-xylulose reductase (NADP+) activity
                                                is-alactaldehyde reductase (NADPH) activity
                                                is-alactaldehyde reductase activity +
                                                is-along-chain-alcohol dehydrogenase activity
                                                is-amalate dehydrogenase (decarboxylating) (NAD+) activity
                                                is-amalate dehydrogenase (decarboxylating) (NADP+) activity
                                                is-amalate dehydrogenase (NADP+) activity
                                                is-amannitol 2-dehydrogenase (NADP+) activity
                                                is-amannitol 2-dehydrogenase activity
                                                is-amannitol dehydrogenase activity
                                                is-amannitol-1-phosphate 5-dehydrogenase activity
                                                is-amannose-6-phosphate 6-reductase activity
                                                is-amannuronate reductase activity
                                                is-amethanol dehydrogenase activity
                                                is-amethylglyoxal reductase (NADH-dependent) activity
                                                is-amethylglyoxal reductase (NADPH-dependent) activity
                                                is-amethylglyoxal reductase (NADPH-dependent, acetol producing)
                                                is-amevaldate reductase activity +
                                                is-amorphine 6-dehydrogenase activity
                                                is-aN-acetylhexosamine 1-dehydrogenase activity
                                                is-aN-acylmannosamine 1-dehydrogenase activity
                                                is-aoctanol dehydrogenase activity
                                                is-aomega-hydroxydecanoate dehydrogenase activity
                                                is-aoxaloglycolate reductase (decarboxylating) activity
                                                is-apantoate 4-dehydrogenase activity
                                                is-aperillyl-alcohol dehydrogenase activity
                                                is-aphenylcoumaran benzylic ether reductase activity
                                                is-aphosphogluconate 2-dehydrogenase activity
                                                is-aphosphogluconate dehydrogenase (decarboxylating) activity
                                                is-aphosphoglycerate dehydrogenase activity
                                                is-apropanediol-phosphate dehydrogenase activity
                                                is-aprostaglandin D2 11-ketoreductase activity
                                                is-aprostaglandin H2 endoperoxidase reductase activity
                                                is-aprostaglandin-E2 9-reductase activity
                                                is-aprostaglandin-F synthase activity
                                                is-apterocarpin synthase activity
                                                is-apyridoxal 4-dehydrogenase activity
                                                is-aquinate 3-dehydrogenase (NAD+) activity
                                                is-aquinate 3-dehydrogenase (NADP+) activity
                                                is-aretinol dehydrogenase activity [GO:0004745] (19 genes, 22 annotations)
                                                is-aribitol 2-dehydrogenase activity
                                                is-aribitol-5-phosphate 2-dehydrogenase activity
                                                is-aribose 1-dehydrogenase (NADP+) activity
                                                is-aS-(hydroxymethyl)glutathione dehydrogenase activity
                                                is-asalutaridine reductase (NADPH) activity
                                                is-asepiapterin reductase activity
                                                is-asequoyitol dehydrogenase activity
                                                is-aserine 3-dehydrogenase activity
                                                is-ashikimate 3-dehydrogenase (NAD+) activity
                                                is-ashikimate 3-dehydrogenase (NADP+) activity
                                                is-asinapyl alcohol dehydrogenase activity
                                                is-asorbitol-6-phosphate 2-dehydrogenase activity
                                                is-asorbose 5-dehydrogenase (NADP+) activity
                                                is-asorbose reductase activity
                                                is-asteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +
                                                is-asterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
                                                is-asulcatone reductase activity
                                                is-atagaturonate reductase activity
                                                is-atartrate dehydrogenase activity
                                                is-atetrahydroxynaphthalene reductase activity
                                                is-atropine dehydrogenase activity
                                                is-atropinone reductase activity
                                                is-aUDP-4-keto-rhamnose-4-keto-reductase activity
                                                is-aUDP-glucose 6-dehydrogenase activity
                                                is-aUDP-N-acetylglucosamine 6-dehydrogenase activity
                                                is-aUDP-N-acetylmuramate dehydrogenase activity
                                                is-aureidoglycolate dehydrogenase activity
                                                is-auronate dehydrogenase activity
                                                is-avellosimine dehydrogenase activity
                                                is-avery long-chain-3-hydroxyacyl-CoA dehydrogenase activity
                                                is-avomifoliol 4'-dehydrogenase activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory