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Rdh16
Gene Detail
 Symbol
Name
ID
Rdh16
retinol dehydrogenase 16
MGI:1201375
Synonyms cis-retinol/androgen dehydrogenase 1, CRAD1, Rdh6
Feature Type protein coding gene
Genetic Map
Chromosome 10
75.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:127801152-127846565 bp, + strand
From VEGA annotation of GRCm38

  45414 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129514  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 8 western clawed frog; 1 zebrafish

Protein SuperFamily: retinol dehydrogenase
Gene Tree: Rdh16

Human
homologs
Human Homolog RDH16, retinol dehydrogenase 16 (all-trans)
NCBI Gene ID 8608
neXtProt AC  NX_O75452
Human Synonyms  RODH-4, SDR9C8
Human Chr (Location)  12q13.3; chr12:56951431-56959374 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Interactions
Rdh16 interacts with 267 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process 9-cis-retinoic acid biosynthetic process, oxidation-reduction process
Component endoplasmic reticulum lumen, integral component of organelle membrane
Function protein homodimerization activity, retinol dehydrogenase activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (99)    Tissues (99)    Images (4)
Theiler Stages: 9, 11, 13, 15, 22, 28
Assay TypeResults
RNA in situ 94
RT-PCR 5
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) Genomic(5) cDNA(31) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027661 (Evidence)
Ensembl Gene ModelENSMUSG00000069456 (Evidence)
Entrez Gene19683 (Evidence)
UniGene100276
DoTSDT.537420
Consensus CDS ProjectCCDS24252.1
International Mouse Knockout Project StatusRdh16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027661 VEGA Gene Model | MGI Sequence Detail 45414 C57BL/6J ±  kb
transcript OTTMUST00000068442 VEGA | MGI Sequence Detail 3207 Not Applicable 
polypeptide OTTMUSP00000034610 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(229 from dbSNP Build 137)    SNPs within 2kb including multiple locations(243)
Protein-related
information
ResourceIDDescription
InterPro IPR002347 Glucose/ribitol dehydrogenase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020904 Short-chain dehydrogenase/reductase, conserved site
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
References (Earliest) J:44862 Chai X, et al., cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase. J Biol Chem. 1997 Dec 26;272(52):33125-31
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory