Rdh16
Gene Detail

Symbol Name ID

Rdh16 retinol dehydrogenase 16 MGI:1201375

Synonyms

cis-retinol/androgen dehydrogenase 1, CRAD1, Rdh6

Feature Type

protein coding gene

Genetic Map

Chromosome 10

75.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr10:127801152-127846565 bp, + strand From VEGA annotation of GRCm38   45414 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:74505  Vertebrate Homology Class
5 mouse; 1 rat; 1 zebrafish

Protein SuperFamily: retinol dehydrogenase
Gene Tree: Rdh16

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	9-cis-retinoic acid biosynthetic process, oxidation-reduction process
Component	endoplasmic reticulum lumen, integral to organelle membrane
Function	protein homodimerization activity, retinol dehydrogenase activity

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (98)    Tissues (98)    Images (3)
Theiler Stages: 9, 11, 13, 15, 22

Assay Type	Results
RNA in situ	94
RT-PCR	4

cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) Genomic(5) cDNA(9) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027661 (Evidence)
Ensembl Gene Model	ENSMUSG00000069456 (Evidence)
Entrez Gene	19683 (Evidence)
DoTS	DT.537420
Consensus CDS Project	CCDS24252.1
International Mouse Knockout Project Status	Rdh16

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027661	VEGA Gene Model | MGI Sequence Detail	45414	C57BL/6J
transcript	OTTMUST00000068442	VEGA | MGI Sequence Detail	3207	Not Applicable
polypeptide	OTTMUSP00000034610	VEGA | MGI Sequence Detail	317	Not Applicable

All sequences(27) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(69 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002347	Glucose/ribitol dehydrogenase
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR020904	Short-chain dehydrogenase/reductase, conserved site
InterPro	IPR002198	Short-chain dehydrogenase/reductase SDR

References

(Earliest) J:44862 Chai X, et al., cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase. J Biol Chem. 1997 Dec 26;272(52):33125-31
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)