Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RASGRP3
  • Mouse genes Rasgrp3
  • Rat genes Rasgrp3
  • Zfish genes rasgrp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rasgrp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RASGRP3	IDA		Human	PMID:10934204
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Rasgrp3	IDA		Mouse	PMID:15545601
Molecular Function	GO:0019900	kinase binding	Rasgrp3	IPI	PR:D3YWQ0	Mouse	PMID:15894621
Molecular Function	GO:0005515	protein binding	RASGRP3	IPI	UniProtKB:Q96FJ2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RASGRP3	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RASGRP3	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0031267	small GTPase binding	Rasgrp3	IDA		Mouse	PMID:15545601
Molecular Function	GO:0031267	small GTPase binding	Rasgrp3	IPI	PR:P62835	Mouse	PMID:15894621
Cellular Component	GO:0005737	cytoplasm	Rasgrp3	IDA		Mouse	PMID:15545601
Cellular Component	GO:0005737	cytoplasm	Rasgrp3	IDA		Mouse	PMID:15894621
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	Rasgrp3	IDA		Mouse	PMID:15894621
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rasgrp3	IDA		Mouse	PMID:15894621
Biological Process	GO:0007265	Ras protein signal transduction	Rasgrp3	IDA		Mouse	PMID:15545601
Biological Process	GO:0043087	regulation of GTPase activity	Rasgrp3	IDA		Mouse	PMID:15545601

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern