Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RANGRF
  • Mouse genes Rangrf
  • Rat genes Rangrf
  • Zfish genes rangrf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rangrf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Rangrf	IDA		Mouse	PMID:10811801
Molecular Function	GO:0031267	small GTPase binding	RANGRF	IPI	UniProtKB:P62826	Human	PMID:11290418
Molecular Function	GO:0031267	small GTPase binding	RANGRF	IPI	UniProtKB:P62826	Human	PMID:29040603
Molecular Function	GO:0031267	small GTPase binding	Rangrf	IDA		Mouse	PMID:10811801
Molecular Function	GO:0017080	sodium channel regulator activity	RANGRF	IDA		Human	PMID:18184654
Molecular Function	GO:0017080	sodium channel regulator activity	RANGRF	IMP		Human	PMID:23420830
Molecular Function	GO:0017080	sodium channel regulator activity	Rangrf	IMP		Mouse	MGI:MGI:5508678|PMID:23420830
Molecular Function	GO:0044325	transmembrane transporter binding	RANGRF	IPI	UniProtKB:Q14524	Human	PMID:18184654
Molecular Function	GO:0044325	transmembrane transporter binding	Rangrf	IPI	UniProtKB:Q9JJV9	Mouse	MGI:MGI:5426778|PMID:18184654
Cellular Component	GO:0005901	caveola	RANGRF	IDA		Human	PMID:23420830
Cellular Component	GO:0005737	cytoplasm	RANGRF	IDA		Human	PMID:11290418
Cellular Component	GO:0005829	cytosol	RANGRF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014704	intercalated disc	Rangrf	IDA		Mouse	MGI:MGI:5426778|PMID:18184654
Cellular Component	GO:0005654	nucleoplasm	RANGRF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Rangrf	IDA		Mouse	PMID:10811801
Cellular Component	GO:0005634	nucleus	RANGRF	IDA		Human	PMID:11290418
Cellular Component	GO:0005634	nucleus	RANGRF	HDA		Human	PMID:21630459
Cellular Component	GO:0005791	rough endoplasmic reticulum	RANGRF	IDA		Human	PMID:23420830
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:0060047	heart contraction	rangrf	IMP	ZFIN:ZDB-MRPHLNO-171206-7	Zfish	PMID:26903377
Biological Process	GO:0060047	heart contraction	rangrf	IMP	ZFIN:ZDB-MRPHLNO-171206-8	Zfish	PMID:26903377
Biological Process	GO:0001947	heart looping	rangrf	IMP	ZFIN:ZDB-MRPHLNO-171206-8	Zfish	PMID:26903377
Biological Process	GO:0001947	heart looping	rangrf	IMP	ZFIN:ZDB-MRPHLNO-171206-7	Zfish	PMID:26903377
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	RANGRF	IDA		Human	PMID:18184654
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:0032527	protein exit from endoplasmic reticulum	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:0098905	regulation of bundle of His cell action potential	RANGRF	IMP		Human	PMID:21621375
Biological Process	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction	RANGRF	IMP		Human	PMID:21621375
Biological Process	GO:0003254	regulation of membrane depolarization	RANGRF	IDA		Human	PMID:18184654
Biological Process	GO:0003254	regulation of membrane depolarization	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:0003254	regulation of membrane depolarization	Rangrf	IMP		Mouse	MGI:MGI:5508678|PMID:23420830
Biological Process	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential	RANGRF	IMP		Human	PMID:21621375
Biological Process	GO:0042391	regulation of membrane potential	RANGRF	IDA		Human	PMID:18184654
Biological Process	GO:0090226	regulation of microtubule nucleation by Ran protein signal transduction	RANGRF	IMP		Human	PMID:29040603
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	RANGRF	IDA		Human	PMID:18184654
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	RANGRF	IMP		Human	PMID:21621375
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	Rangrf	IMP		Mouse	MGI:MGI:5508678|PMID:23420830
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	RANGRF	IDA		Human	PMID:18184654
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	RANGRF	IMP		Human	PMID:21621375
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	RANGRF	IMP		Human	PMID:23420830
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	Rangrf	IMP		Mouse	MGI:MGI:5508678|PMID:23420830

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern