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Rangrf Gene Detail
Summary
  • Symbol
    Rangrf
  • Name
    RAN guanine nucleotide release factor
  • Synonyms
    2400006H24Rik, Mog1, Rangnrf
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889073
    NCBI Gene: 57785
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:68972484-68975185 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.24 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889073
protein coding gene Chr11:68972484-68975185 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018511
protein coding gene Chr11:69363835-69366959 (-)
A/J MGP_AJ_G0018480
protein coding gene Chr11:66762193-66764894 (-)
AKR/J MGP_AKRJ_G0018449
protein coding gene Chr11:68757488-68760736 (-)
BALB/cJ MGP_BALBcJ_G0018451
protein coding gene Chr11:67080191-67083868 (-)
C3H/HeJ MGP_C3HHeJ_G0018264
protein coding gene Chr11:68777643-68781643 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018903
protein coding gene Chr11:71474880-71477718 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016547
protein coding gene Chr11:63699368-63702091 (-)
CAST/EiJ MGP_CASTEiJ_G0017820
protein coding gene Chr11:69014433-69015855 (-)
CBA/J MGP_CBAJ_G0018238
protein coding gene Chr11:74665349-74668050 (-)
DBA/2J MGP_DBA2J_G0018347
protein coding gene Chr11:66359285-66361385 (-)
FVB/NJ MGP_FVBNJ_G0018337
protein coding gene Chr11:65979109-65982219 (-)
LP/J MGP_LPJ_G0018418
protein coding gene Chr11:69945903-69950031 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018360
protein coding gene Chr11:75319344-75323340 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018944
protein coding gene Chr11:69003620-69006355 (-)
PWK/PhJ MGP_PWKPhJ_G0017595
protein coding gene Chr11:66989718-66992760 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017383
protein coding gene Chr11:68824047-68826757 (-)
WSB/EiJ MGP_WSBEiJ_G0017873
protein coding gene Chr11:68646853-68649753 (-)



Homology
more
  • Human Ortholog
    RANGRF, RAN guanine nucleotide release factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RANGRF, RAN guanine nucleotide release factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC165, HSPC236, MOG1, RANGNRF
  • Links
    NCBI Gene ID: 29098
    neXtProt AC: NX_Q9HD47
    UniProt: Q9HD47

  • Chr Location
    17p13.1; chr17:8287150-8290091 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57785 NCBI Gene Model | MGI Sequence Detail 2702 C57BL/6J ±  kb
transcript NM_021329 RefSeq | MGI Sequence Detail 845 C57BL/6  
polypeptide Q9JIB0 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913665
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:200449 Chakrabarti S, et al., MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):392-401

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory