Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RALGAPA2
  • Mouse genes Ralgapa2
  • Rat genes Ralgapa2
  • Zfish genes ralgapa2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ralgapa2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	Ralgapa2	IGI	MGI:MGI:2444531	Mouse	PMID:21148297
Molecular Function	GO:0005096	GTPase activator activity	Ralgapa2	IDA		Rat	PMID:19520869|RGD:8553279
Molecular Function	GO:0005515	protein binding	RALGAPA2	IPI	UniProtKB:Q8WTU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ralgapa2	IPI	PR:Q9CR56	Mouse	PMID:25220458
Molecular Function	GO:0005515	protein binding	Ralgapa2	IPI	PR:Q8CEC5	Mouse	PMID:25220458
Molecular Function	GO:0046982	protein heterodimerization activity	Ralgapa2	IPI	UniProtKB:P86410	Rat	PMID:19520869|RGD:8553279
Cellular Component	GO:0005737	cytoplasm	RALGAPA2	IDA		Human	PMID:16490346
Cellular Component	GO:0005829	cytosol	RALGAPA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	RALGAPA2	HDA		Human	PMID:22664934
Cellular Component	GO:0005886	plasma membrane	RALGAPA2	IDA		Human	GO_REF:0000052
Biological Process	GO:0090630	activation of GTPase activity	Ralgapa2	IGI	MGI:MGI:2444531	Mouse	PMID:21148297
Biological Process	GO:0090630	activation of GTPase activity	Ralgapa2	IDA		Rat	PMID:19520869|RGD:8553279
Biological Process	GO:0032484	Ral protein signal transduction	Ralgapa2	IMP		Mouse	PMID:21148297
Biological Process	GO:0060178	regulation of exocyst localization	Ralgapa2	IMP		Mouse	PMID:21148297
Biological Process	GO:0032880	regulation of protein localization	Ralgapa2	IMP		Mouse	PMID:21148297

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern