Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAD18
  • Mouse genes Rad18
  • Rat genes Rad18
  • Zfish genes rad18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rad18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	RAD18	IDA		Human	PMID:25023518
Molecular Function	GO:0140678	molecular function inhibitor activity	RAD18	EXP		Human	PMID:21422291
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	RAD18	IDA		Human	PMID:22742833
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q14527	Human	PMID:18316726
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q14527	Human	PMID:18719106
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P49459	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P63146	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P63146	Human	PMID:21422291
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q9BSD3	Human	PMID:21659603
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q8R3P9	Human	PMID:22036607
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q9H040	Human	PMID:22681887
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P49459	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q8IX21	Human	PMID:25931565
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q9BQI6	Human	PMID:25931565
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P49459	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P43358	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P63146	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:O14737	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P43358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q13416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q96B67	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAD18	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rad18	IPI	PR:P63147	Mouse	PMID:12509447
Molecular Function	GO:0005515	protein binding	Rad18	IPI	PR:Q9Z255	Mouse	PMID:12509447
Molecular Function	GO:0044877	protein-containing complex binding	RAD18	IPI	UniProtKB:Q8IY18	Human	PMID:25931565
Molecular Function	GO:0044877	protein-containing complex binding	RAD18	IPI	UniProtKB:Q96SB8	Human	PMID:25931565
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RAD18	IPI	UniProtKB:P49459	Human	PMID:10908344
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RAD18	IPI	UniProtKB:P63146	Human	PMID:10908344
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RAD18	IPI	UniProtKB:P63146	Human	PMID:18363965
Molecular Function	GO:0000403	Y-form DNA binding	RAD18	IDA		Human	PMID:18363965
Cellular Component	GO:0005813	centrosome	RAD18	IDA		Human	PMID:15632077
Cellular Component	GO:0000785	chromatin	Rad18	IDA		Mouse	PMID:15657431
Cellular Component	GO:0001673	male germ cell nucleus	Rad18	IDA		Mouse	PMID:19068231
Cellular Component	GO:0016604	nuclear body	RAD18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0042405	nuclear inclusion body	RAD18	IDA		Human	PMID:22036607
Cellular Component	GO:0005654	nucleoplasm	RAD18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RAD18	IDA		Human	PMID:15632077
Cellular Component	GO:0005634	nucleus	RAD18	IDA		Human	PMID:22036607
Cellular Component	GO:0005634	nucleus	RAD18	IDA		Human	PMID:25023518
Cellular Component	GO:0005634	nucleus	Rad18	IDA		Mouse	PMID:11013078
Cellular Component	GO:0005657	replication fork	RAD18	IDA		Human	PMID:18363965
Cellular Component	GO:0035861	site of double-strand break	RAD18	IDA		Human	PMID:25931565
Cellular Component	GO:0001741	XY body	Rad18	IDA		Mouse	PMID:15383616
Biological Process	GO:0006974	DNA damage response	RAD18	IDA		Human	PMID:25023518
Biological Process	GO:0006974	DNA damage response	RAD18	IDA		Human	PMID:22036607
Biological Process	GO:0006974	DNA damage response	RAD18	IDA		Human	PMID:25931565
Biological Process	GO:0006974	DNA damage response	Rad18	IMP	MGI:MGI:3835812	Mouse	PMID:12509447
Biological Process	GO:0060548	negative regulation of cell death	RAD18	IDA		Human	PMID:22036607
Biological Process	GO:0045910	negative regulation of DNA recombination	Rad18	IMP	MGI:MGI:3835812	Mouse	PMID:12509447
Biological Process	GO:0051984	positive regulation of chromosome segregation	RAD18	IMP		Human	PMID:25931565
Biological Process	GO:0051865	protein autoubiquitination	RAD18	IDA		Human	PMID:25023518
Biological Process	GO:0009411	response to UV	Rad18	IMP	MGI:MGI:3835812	Mouse	PMID:12509447
Biological Process	GO:0007283	spermatogenesis	Rad18	IMP	MGI:MGI:3835812	Mouse	PMID:19068231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern