Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB3GAP1
  • Mouse genes Rab3gap1
  • Rat genes Rab3gap1
  • Zfish genes rab3gap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab3gap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RAB3GAP1	IDA		Human	PMID:10859313
Molecular Function	GO:0005096	GTPase activator activity	RAB3GAP1	IDA		Human	PMID:16923123
Molecular Function	GO:0005096	GTPase activator activity	RAB3GAP1	IMP		Human	PMID:24891604
Molecular Function	GO:0005096	GTPase activator activity	RAB3GAP1	IDA		Human	PMID:9030515
Molecular Function	GO:0005096	GTPase activator activity	Rab3gap1	IDA		Rat	PMID:9733780|RGD:8553935
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RAB3GAP1	IMP		Human	PMID:24891604
Molecular Function	GO:0005515	protein binding	RAB3GAP1	IPI	UniProtKB:P49257	Human	PMID:22337587
Molecular Function	GO:0005515	protein binding	RAB3GAP1	IPI	UniProtKB:Q9BZV1	Human	PMID:22337587
Molecular Function	GO:0005515	protein binding	Rab3gap1	IPI	UniProtKB:Q5U1Z0	Rat	PMID:9733780|RGD:8553935
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:P20336	Human	PMID:10859313
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:P20336	Human	PMID:24891604
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:P20337	Human	PMID:24891604
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:P20339	Human	PMID:24891604
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:Q86YS6	Human	PMID:24891604
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:Q96E17	Human	PMID:24891604
Molecular Function	GO:0031267	small GTPase binding	RAB3GAP1	IPI	UniProtKB:Q9NP72	Human	PMID:24891604
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	RAB3GAP1	IDA		Human	PMID:24891604
Cellular Component	GO:0060076	excitatory synapse	Rab3gap1	IDA		Rat	PMID:19730411|RGD:8554379
Cellular Component	GO:0070062	extracellular exosome	RAB3GAP1	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	RAB3GAP1	IDA		Human	PMID:25495476
Cellular Component	GO:0005811	lipid droplet	RAB3GAP1	IDA		Human	PMID:25495476
Cellular Component	GO:0032991	protein-containing complex	RAB3GAP1	IDA		Human	PMID:24891604
Biological Process	GO:0007420	brain development	RAB3GAP1	IMP		Human	PMID:20512159
Biological Process	GO:0043010	camera-type eye development	RAB3GAP1	IMP		Human	PMID:20512159
Biological Process	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane	RAB3GAP1	IMP		Human	PMID:24891604
Biological Process	GO:0060079	excitatory postsynaptic potential	Rab3gap1	IMP		Mouse	MGI:MGI:3652690|PMID:16782817
Biological Process	GO:0060325	face morphogenesis	RAB3GAP1	IMP		Human	PMID:20512159
Biological Process	GO:0021854	hypothalamus development	RAB3GAP1	IMP		Human	PMID:20512159
Biological Process	GO:0034389	lipid droplet organization	RAB3GAP1	IMP		Human	PMID:24239381
Biological Process	GO:2000786	positive regulation of autophagosome assembly	RAB3GAP1	IMP		Human	PMID:25495476
Biological Process	GO:1903373	positive regulation of endoplasmic reticulum tubular network organization	RAB3GAP1	IMP		Human	PMID:24891604
Biological Process	GO:0010628	positive regulation of gene expression	Rab3gap1	IDA		Mouse	MGI:MGI:3652690|PMID:16782817
Biological Process	GO:0061646	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization	Rab3gap1	IMP		Mouse	MGI:MGI:3652690|PMID:16782817
Biological Process	GO:0043547	positive regulation of GTPase activity	RAB3GAP1	IMP		Human	PMID:24891604
Biological Process	GO:0043547	positive regulation of GTPase activity	Rab3gap1	IMP		Mouse	MGI:MGI:3652690|PMID:16782817
Biological Process	GO:1903061	positive regulation of protein lipidation	RAB3GAP1	IMP		Human	PMID:25495476
Biological Process	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter	Rab3gap1	IMP		Mouse	MGI:MGI:3652690|PMID:16782817
Biological Process	GO:0043087	regulation of GTPase activity	RAB3GAP1	IDA		Human	PMID:10859313
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	Rab3gap1	IMP		Mouse	MGI:MGI:3652690|PMID:16782817

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern