Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes QDPR
  • Mouse genes Qdpr
  • Rat genes Qdpr
  • Zfish genes qdpra,qdprb.1,qdprb.2,qdprb.3,qdprb.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Qdpr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004155	6,7-dihydropteridine reductase activity	QDPR	IDA		Human	PMID:3033643
Molecular Function	GO:0004155	6,7-dihydropteridine reductase activity	Qdpr	IMP		Rat	PMID:1898002|RGD:8553309
Molecular Function	GO:0004155	6,7-dihydropteridine reductase activity	Qdpr	IDA		Rat	PMID:660556|RGD:4139903
Molecular Function	GO:0004155	6,7-dihydropteridine reductase activity	Qdpr	IMP		Rat	PMID:8262916|RGD:5128590
Molecular Function	GO:0004155	6,7-dihydropteridine reductase activity	qdprb.1	IDA		Zfish	PMID:30995231
Molecular Function	GO:0042802	identical protein binding	Qdpr	IPI	RGD:619915	Rat	PMID:1631094|RGD:5128584
Molecular Function	GO:0070404	NADH binding	Qdpr	IPI	PubChem_Compound:439153	Rat	PMID:8631945|RGD:5128583
Molecular Function	GO:0070402	NADPH binding	Qdpr	IMP		Rat	PMID:1639779|RGD:5128591
Cellular Component	GO:0005737	cytoplasm	QDPR	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005829	cytosol	Qdpr	IDA		Rat	PMID:3477172|RGD:5128605
Cellular Component	GO:0070062	extracellular exosome	QDPR	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	QDPR	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Qdpr	HDA		Mouse	PMID:18614015
Cellular Component	GO:0043005	neuron projection	Qdpr	IDA		Rat	PMID:660556|RGD:4139903
Biological Process	GO:0007420	brain development	qdprb.1	IMP	ZFIN:ZDB-MRPHLNO-190828-6	Zfish	PMID:30995231
Biological Process	GO:0007420	brain development	qdprb.1	IMP	ZFIN:ZDB-MRPHLNO-190828-5	Zfish	PMID:30995231
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Qdpr	IEP		Rat	PMID:2484967|RGD:5128599
Biological Process	GO:0042063	gliogenesis	qdprb.1	IMP	ZFIN:ZDB-MRPHLNO-190828-5	Zfish	PMID:30995231
Biological Process	GO:0006541	glutamine metabolic process	qdprb.1	IMP	ZFIN:ZDB-MRPHLNO-190828-5	Zfish	PMID:30995231
Biological Process	GO:0006559	L-phenylalanine catabolic process	Qdpr	IEP		Rat	PMID:4155291|RGD:5128604
Biological Process	GO:0006558	L-phenylalanine metabolic process	qdpra	IMP	ZFIN:ZDB-MRPHLNO-190828-4	Zfish	PMID:30995231
Biological Process	GO:0001889	liver development	Qdpr	IEP		Rat	PMID:710385|RGD:5128606
Biological Process	GO:0042438	melanin biosynthetic process	qdpra	IMP	ZFIN:ZDB-MRPHLNO-190828-4	Zfish	PMID:30995231
Biological Process	GO:0010044	response to aluminum ion	Qdpr	IEP		Rat	PMID:3477172|RGD:5128605
Biological Process	GO:0033762	response to glucagon	Qdpr	IEP		Rat	PMID:4155291|RGD:5128604
Biological Process	GO:0010288	response to lead ion	Qdpr	IEP		Rat	PMID:3815851|RGD:5128602
Biological Process	GO:0006729	tetrahydrobiopterin biosynthetic process	Qdpr	IMP		Rat	PMID:1898002|RGD:8553309
Biological Process	GO:0006729	tetrahydrobiopterin biosynthetic process	Qdpr	IDA		Rat	PMID:660556|RGD:4139903
Biological Process	GO:0006729	tetrahydrobiopterin biosynthetic process	Qdpr	IMP		Rat	PMID:9235988|RGD:5128582

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern