Qdpr
Gene Detail

Symbol Name ID

Qdpr quinoid dihydropteridine reductase MGI:97836

Synonyms

2610008L04Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

24.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(21)

Sequence Map

Chr5:45434032-45450235 bp, - strand From VEGA annotation of GRCm38   16204 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:271  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dihydropteridine reductase
Gene Tree: Qdpr

Human homologs

Human Homolog		QDPR, quinoid dihydropteridine reductase
NCBI Gene ID		5860
neXtProt AC		NX_P09417
Human Synonyms		DHPR, PKU2, SDR33C1
Human Chr (Location)		4p15.31; chr4:17488016-17513857 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human QDPR

Alleles and phenotypes

All alleles(5) : Targeted(4) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	metabolic process, tetrahydrobiopterin biosynthetic process
Component	cytoplasm, cytosol, ...
Function	6,7-dihydropteridine reductase activity, NADH binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (111)    Tissues (96)    Images (21)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	111

cDNA source data(137)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(141) cDNA(138) Primer pair(2) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027775 (Evidence)
Ensembl Gene Model	ENSMUSG00000015806 (Evidence)
Entrez Gene	110391 (Evidence)
UniGene	30204
DFCI	TC1572062
DoTS	DT.535975, DT.94203582
NIA Mouse Gene Index	U026168
EC	1.5.1.34
Consensus CDS Project	CCDS19272.1
International Mouse Knockout Project Status	Qdpr

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027775	VEGA Gene Model | MGI Sequence Detail	16204	C57BL/6J
transcript	OTTMUST00000068743	VEGA | MGI Sequence Detail	1400	Not Applicable
polypeptide	OTTMUSP00000034817	VEGA | MGI Sequence Detail	241	Not Applicable

All sequences(51) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(9) : SNPs(120 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR020904	Short-chain dehydrogenase/reductase, conserved site
InterPro	IPR002198	Short-chain dehydrogenase/reductase SDR
Protein Ontology	PR:000013562	dihydropteridine reductase

References

(Earliest) J:8865 MacDonald ME, et al., Physical and genetic localization of quinonoid dihydropteridine reductase gene (QDPR) on short arm of chromosome 4. Somat Cell Mol Genet. 1987 Sep;13(5):569-74
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(57)

Other accession IDs

MGD-MRK-13735, MGI:1196320, MGI:1917283