Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRR7
  • Mouse genes Prr7
  • Rat genes Prr7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prr7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036041	long-chain fatty acid binding	PRR7	IMP		Human	PMID:21460222
Molecular Function	GO:0005515	protein binding	PRR7	IPI	UniProtKB:P05412	Human	PMID:27458189
Molecular Function	GO:0005515	protein binding	Prr7	IPI	UniProtKB:P31016	Rat	PMID:27458189|RGD:13702279
Molecular Function	GO:1990782	protein tyrosine kinase binding	PRR7	IPI	UniProtKB:P12931	Human	PMID:21460222
Molecular Function	GO:0044877	protein-containing complex binding	Prr7	IPI	UniProtKB:P35439	Rat	PMID:27458189|RGD:13702279
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	PRR7	IPI	UniProtKB:Q969H0	Human	PMID:27458189
Cellular Component	GO:0005829	cytosol	PRR7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	Prr7	IDA		Rat	PMID:15629447|RGD:1579799
Cellular Component	GO:0098978	glutamatergic synapse	Prr7	IMP		Rat	PMID:15629447|RGD:1579799
Cellular Component	GO:0098978	glutamatergic synapse	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Cellular Component	GO:0098978	glutamatergic synapse	Prr7	IMP		Rat	PMID:27458189|RGD:13702279
Cellular Component	GO:0043005	neuron projection	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Cellular Component	GO:0005654	nucleoplasm	PRR7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PRR7	IMP		Human	PMID:21460222
Cellular Component	GO:0005886	plasma membrane	PRR7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PRR7	IMP		Human	PMID:21460222
Cellular Component	GO:0014069	postsynaptic density	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Prr7	IDA		Rat	PMID:15629447|RGD:1579799
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Prr7	IMP		Rat	PMID:15629447|RGD:1579799
Cellular Component	GO:0045202	synapse	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Biological Process	GO:0046632	alpha-beta T cell differentiation	Prr7	IMP	MGI:MGI:4399196	Mouse	PMID:27657535
Biological Process	GO:0031397	negative regulation of protein ubiquitination	PRR7	IMP		Human	PMID:27458189
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Prr7	IMP		Rat	PMID:27458189|RGD:13702279
Biological Process	GO:0043065	positive regulation of apoptotic process	PRR7	IMP		Human	PMID:21460222
Biological Process	GO:0010942	positive regulation of cell death	PRR7	IMP		Human	PMID:27458189
Biological Process	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	PRR7	IMP		Human	PMID:21460222
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Prr7	IDA		Rat	PMID:27458189|RGD:13702279
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Prr7	IMP		Rat	PMID:27458189|RGD:13702279
Biological Process	GO:0033077	T cell differentiation in thymus	Prr7	IMP	MGI:MGI:4399196	Mouse	PMID:27657535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern