Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PROP1
  • Mouse genes Prop1
  • Rat genes Prop1
  • Zfish genes prop1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prop1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Prop1	IPI	PR:Q02248	Mouse	PMID:16678101
Molecular Function	GO:0003682	chromatin binding	Prop1	IDA		Mouse	PMID:16678101
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Prop1	IDA		Mouse	MGI:MGI:3690195|PMID:16678101
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Prop1	IDA		Mouse	MGI:MGI:3690195|PMID:16678101
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q08117	Human	PMID:23732115
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:A5LHX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:A6NJ78-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P05813	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P15289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P28070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P63165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q3LI70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q3SYF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q53HV7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q5TA45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q69YG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6J272	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6NSM0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6NVU6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6P1W5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6UXA7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q6YFQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q7RTU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q7Z4N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8IUB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8IUC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8IWZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8N1L9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8N6F8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8NCR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8NFV4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8TDS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q92567-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q96A09	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q96CS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q96F45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q96M29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q9BSH5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q9GZM7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q9H5F2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q9Y458	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROP1	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Prop1	IPI	PR:Q02248	Mouse	PMID:16678101
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Prop1	IDA		Mouse	MGI:MGI:3690195|PMID:16678101
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PROP1	IDA		Human	PMID:28473536
Cellular Component	GO:0005667	transcription regulator complex	Prop1	IDA		Mouse	PMID:16678101
Biological Process	GO:0021984	adenohypophysis development	Prop1	IMP		Mouse	PMID:18996108
Biological Process	GO:0021984	adenohypophysis development	prop1	IMP	ZFIN:ZDB-MRPHLNO-110620-1	Zfish	PMID:21362424
Biological Process	GO:0009887	animal organ morphogenesis	Prop1	IMP	MGI:MGI:3521736	Mouse	PMID:15459176
Biological Process	GO:0009887	animal organ morphogenesis	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:12183375
Biological Process	GO:0006915	apoptotic process	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:16556738
Biological Process	GO:0001568	blood vessel development	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:16556738
Biological Process	GO:0016477	cell migration	Prop1	IGI	MGI:MGI:104853	Mouse	PMID:18996108
Biological Process	GO:0009953	dorsal/ventral pattern formation	Prop1	IMP	MGI:MGI:3521736	Mouse	PMID:15459176
Biological Process	GO:0009953	dorsal/ventral pattern formation	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:12183375
Biological Process	GO:0048732	gland development	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:16556738
Biological Process	GO:0048850	hypophysis morphogenesis	Prop1	IMP	MGI:MGI:3690463	Mouse	PMID:16678101
Biological Process	GO:0021979	hypothalamus cell differentiation	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:9067988
Biological Process	GO:0043066	negative regulation of apoptotic process	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:16556738
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Prop1	IDA		Mouse	PMID:16678101
Biological Process	GO:0021983	pituitary gland development	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:11731482
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Prop1	IGI	MGI:MGI:88276	Mouse	PMID:16678101
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Prop1	IDA		Mouse	PMID:16678101
Biological Process	GO:0060126	somatotropin secreting cell differentiation	Prop1	IMP	MGI:MGI:1856842	Mouse	PMID:6194978

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern