Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKG2
  • Mouse genes Prkg2
  • Rat genes Prkg2
  • Zfish genes prkg2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004692	cGMP-dependent protein kinase activity	PRKG2	IMP		Human	PMID:33106379
Molecular Function	GO:0004692	cGMP-dependent protein kinase activity	Prkg2	IDA		Rat	PMID:7589584|RGD:7777109
Molecular Function	GO:0042802	identical protein binding	Prkg2	IPI	RGD:3401	Rat	PMID:9115239|RGD:7777117
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	PRKG2	IMP		Human	PMID:33106379
Molecular Function	GO:0005515	protein binding	Prkg2	IPI	PR:P62492	Mouse	PMID:18656450
Molecular Function	GO:0005515	protein binding	Prkg2	IPI	PR:P46638	Mouse	PMID:18656450
Molecular Function	GO:0106310	protein serine kinase activity	PRKG2	IMP		Human	PMID:33106379
Cellular Component	GO:0016020	membrane	Prkg2	IDA		Rat	PMID:9115239|RGD:7777117
Cellular Component	GO:0031965	nuclear membrane	Prkg2	IDA		Rat	PMID:18474265|RGD:7775066
Cellular Component	GO:0005886	plasma membrane	Prkg2	IDA		Mouse	PMID:18656450
Biological Process	GO:0071476	cellular hypotonic response	Prkg2	IDA		Mouse	MGI:MGI:5882897|PMID:15905169
Biological Process	GO:0032922	circadian regulation of gene expression	Prkg2	IMP	MGI:MGI:2449704	Mouse	PMID:12725729
Biological Process	GO:0007623	circadian rhythm	Prkg2	IMP	MGI:MGI:2449704	Mouse	PMID:12725729
Biological Process	GO:0045794	negative regulation of cell volume	Prkg2	IGI	UniProtKB:Q61189	Mouse	MGI:MGI:5882897|PMID:15905169
Biological Process	GO:2001226	negative regulation of chloride transport	Prkg2	IDA		Rat	PMID:15905169|RGD:12793036
Biological Process	GO:0036289	peptidyl-serine autophosphorylation	Prkg2	IDA		Rat	PMID:12764134|RGD:1299018
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Prkg2	IGI	RGD:733228	Rat	PMID:15466490|RGD:150429792
Biological Process	GO:1903829	positive regulation of protein localization	Prkg2	IGI	RGD:733228	Rat	PMID:15466490|RGD:150429792
Biological Process	GO:0072659	protein localization to plasma membrane	Prkg2	IMP		Rat	PMID:15872007|RGD:7775059
Biological Process	GO:0006468	protein phosphorylation	PRKG2	IMP		Human	PMID:15905169
Biological Process	GO:0006468	protein phosphorylation	PRKG2	IMP		Human	PMID:33106379
Biological Process	GO:0007165	signal transduction	PRKG2	IMP		Human	PMID:33106379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern