Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PMPCA
  • Mouse genes Pmpca
  • Rat genes Pmpca
  • Zfish genes pmpca
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pmpca

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	Pmpca	IDA		Rat	PMID:2236012|RGD:1299588
Molecular Function	GO:0008237	metallopeptidase activity	Pmpca	IDA		Rat	PMID:7490252|RGD:13463461
Molecular Function	GO:0005515	protein binding	PMPCA	IPI	UniProtKB:P36508	Human	PMID:32296183
Cellular Component	GO:0005615	extracellular space	PMPCA	HDA		Human	PMID:22664934
Cellular Component	GO:0005743	mitochondrial inner membrane	PMPCA	IDA		Human	PMID:25808372
Cellular Component	GO:0005739	mitochondrion	PMPCA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PMPCA	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	Pmpca	HDA		Mouse	PMID:18614015
Biological Process	GO:0016485	protein processing	Pmpca	IDA		Rat	PMID:2236012|RGD:1299588
Biological Process	GO:0006627	protein processing involved in protein targeting to mitochondrion	PMPCA	IDA		Human	PMID:22354088
Biological Process	GO:0006627	protein processing involved in protein targeting to mitochondrion	PMPCA	IMP		Human	PMID:25808372

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern