Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLTP
  • Mouse genes Pltp
  • Rat genes Pltp
  • Zfish genes pltp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pltp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097001	ceramide binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0140340	cerebroside transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0120020	cholesterol transfer activity	Pltp	IMP		Mouse	MGI:MGI:1332889|PMID:10079112
Molecular Function	GO:0140337	diacylglyceride transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0019992	diacylglycerol binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0008035	high-density lipoprotein particle binding	PLTP	IDA		Human	PMID:29883800
Molecular Function	GO:0030169	low-density lipoprotein particle binding	PLTP	IDA		Human	PMID:29883800
Molecular Function	GO:0070300	phosphatidic acid binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:1990050	phosphatidic acid transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0031210	phosphatidylcholine binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	Pltp	IMP		Mouse	MGI:MGI:1332889|PMID:10079112
Molecular Function	GO:0008429	phosphatidylethanolamine binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	Pltp	IMP		Mouse	MGI:MGI:1332889|PMID:10079112
Molecular Function	GO:1901611	phosphatidylglycerol binding	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0140339	phosphatidylglycerol transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0008526	phosphatidylinositol transfer activity	Pltp	IMP		Mouse	MGI:MGI:1332889|PMID:10079112
Molecular Function	GO:0120014	phospholipid transfer activity	PLTP	IDA		Human	PMID:11013307
Molecular Function	GO:0120014	phospholipid transfer activity	PLTP	IDA		Human	PMID:19321130
Molecular Function	GO:0120014	phospholipid transfer activity	PLTP	IMP		Human	PMID:21515415
Molecular Function	GO:0120014	phospholipid transfer activity	PLTP	IDA		Human	PMID:29883800
Molecular Function	GO:0120014	phospholipid transfer activity	PLTP	IDA		Human	PMID:7654777
Molecular Function	GO:0120014	phospholipid transfer activity	Pltp	IDA		Mouse	MGI:MGI:74635|PMID:7615508
Molecular Function	GO:0120014	phospholipid transfer activity	Pltp	IDA		Mouse	MGI:MGI:75991|PMID:7654777
Molecular Function	GO:0140338	sphingomyelin transfer activity	PLTP	IDA		Human	PMID:9132017
Molecular Function	GO:0140338	sphingomyelin transfer activity	Pltp	IMP		Mouse	MGI:MGI:1332889|PMID:10079112
Molecular Function	GO:0034189	very-low-density lipoprotein particle binding	PLTP	IDA		Human	PMID:29883800
Cellular Component	GO:0005576	extracellular region	PLTP	IDA		Human	PMID:19321130
Cellular Component	GO:0005615	extracellular space	PLTP	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Pltp	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0034364	high-density lipoprotein particle	PLTP	IDA		Human	PMID:9132017
Cellular Component	GO:0005634	nucleus	PLTP	IDA		Human	PMID:19321130
Biological Process	GO:0035627	ceramide transport	PLTP	IDA		Human	PMID:9132017
Biological Process	GO:0030317	flagellated sperm motility	Pltp	IMP	MGI:MGI:2176342	Mouse	PMID:16467369
Biological Process	GO:0046836	glycolipid transport	PLTP	IDA		Human	PMID:9132017
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	PLTP	IDA		Human	PMID:24369175
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	PLTP	IDA		Human	PMID:29883800
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	PLTP	IDA		Human	PMID:9132017
Biological Process	GO:0006869	lipid transport	PLTP	IDA		Human	PMID:9132017
Biological Process	GO:0015914	phospholipid transport	PLTP	IDA		Human	PMID:9132017
Biological Process	GO:0010875	positive regulation of cholesterol efflux	PLTP	IDA		Human	PMID:24369175
Biological Process	GO:0010189	vitamin E biosynthetic process	Pltp	IMP	MGI:MGI:2176342	Mouse	PMID:16467369

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern