Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHN1
  • Mouse genes Plekhn1
  • Rat genes Plekhn1
  • Zfish genes plekhn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekhn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1901612	cardiolipin binding	PLEKHN1	IDA		Human	PMID:18191643
Molecular Function	GO:0070300	phosphatidic acid binding	PLEKHN1	IDA		Human	PMID:18191643
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	PLEKHN1	IDA		Human	PMID:18191643
Molecular Function	GO:0001786	phosphatidylserine binding	PLEKHN1	IDA		Human	PMID:18191643
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q07021	Human	PMID:18191643
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q15717	Human	PMID:18191643
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:O60711	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q13625-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q8HWS3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q8NA61	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q15717	Human	PMID:27616329
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q5ZXN6	Human	PMID:29433439
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:P55957	Human	PMID:29531808
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:P15884	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q04864	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q13077	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PLEKHN1	IPI	UniProtKB:Q86VP1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Plekhn1	IPI	UniProtKB:P39428	Mouse	MGI:MGI:3688344|PMID:15102471
Cellular Component	GO:0005856	cytoskeleton	PLEKHN1	IDA		Human	PMID:18191643
Cellular Component	GO:0031966	mitochondrial membrane	PLEKHN1	IDA		Human	PMID:18191643
Cellular Component	GO:0031966	mitochondrial membrane	PLEKHN1	IDA		Human	PMID:29180010
Cellular Component	GO:0005739	mitochondrion	PLEKHN1	IDA		Human	PMID:27616329
Cellular Component	GO:0005739	mitochondrion	PLEKHN1	IDA		Human	PMID:29531808
Cellular Component	GO:0005739	mitochondrion	Plekhn1	IDA		Mouse	MGI:MGI:6105829|PMID:27616329
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	PLEKHN1	IDA		Human	PMID:29180010
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	Plekhn1	IDA		Mouse	MGI:MGI:6105829|PMID:27616329
Biological Process	GO:0043065	positive regulation of apoptotic process	PLEKHN1	IMP		Human	PMID:29531808
Biological Process	GO:0001666	response to hypoxia	PLEKHN1	IDA		Human	PMID:29531808

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern