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Plekhn1 Gene Detail
Summary
  • Symbol
    Plekhn1
  • Name
    pleckstrin homology domain containing, family N member 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387630
    NCBI Gene: 231002
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:156221456-156228542 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 88.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387630
protein coding gene Chr4:156221456-156234857 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029251
protein coding gene Chr4:160594602-160601687 (-)
A/J MGP_AJ_G0029216
protein coding gene Chr4:153827557-153834631 (-)
AKR/J MGP_AKRJ_G0029164
protein coding gene Chr4:158019827-158026912 (-)
BALB/cJ MGP_BALBcJ_G0029232
protein coding gene Chr4:154304350-154311424 (-)
C3H/HeJ MGP_C3HHeJ_G0028953
protein coding gene Chr4:158593027-158600101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029681
protein coding gene Chr4:166297094-166304180 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026924
protein coding gene Chr4:146104068-146111503 (-)
CAST/EiJ MGP_CASTEiJ_G0028365
protein coding gene Chr4:156015709-156024197 (-)
CBA/J MGP_CBAJ_G0028915
protein coding gene Chr4:171347454-171354534 (-)
DBA/2J MGP_DBA2J_G0029064
protein coding gene Chr4:153846359-153853433 (-)
FVB/NJ MGP_FVBNJ_G0029027
protein coding gene Chr4:153098301-153105386 (-)
LP/J MGP_LPJ_G0029154
protein coding gene Chr4:160549238-160556312 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029054
protein coding gene Chr4:174117463-174124548 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029713
protein coding gene Chr4:158651666-158658760 (-)
PWK/PhJ MGP_PWKPhJ_G0028085
protein coding gene Chr4:149988104-149995301 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027919
protein coding gene Chr4:152901695-152908816 (-)
WSB/EiJ MGP_WSBEiJ_G0028445
protein coding gene Chr4:158834018-158841069 (-)



Homology
more
  • Human Ortholog
    PLEKHN1, pleckstrin homology domain containing N1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PLEKHN1, pleckstrin homology domain containing N1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLPABP
  • Links
    NCBI Gene ID: 84069
    neXtProt AC: NX_Q494U1
    UniProt: Q494U1

  • Chr Location
    1p36.33; chr1:965820-975108 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231002 NCBI Gene Model | MGI Sequence Detail 7087 C57BL/6J ±  kb
transcript NM_001008233 RefSeq | MGI Sequence Detail 2210 C57BL/6  
polypeptide Q8C886 UniProt | EBI | MGI Sequence Detail 610 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:251603 Nishino T, et al., Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. Biochim Biophys Acta. 2016 Nov;1861(11):1816-1827

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory