Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLCB4
  • Mouse genes Plcb4
  • Rat genes Plcb4
  • Zfish genes plcb4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plcb4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Plcb4	IPI	RGD:70500	Rat	PMID:15582671|RGD:2299872
Molecular Function	GO:0005515	protein binding	PLCB4	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLCB4	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Plcb4	IPI	PR:P11881	Mouse	PMID:15579147
Molecular Function	GO:0005515	protein binding	Plcb4	IPI	PR:Q9Z2Y3	Mouse	PMID:15579147
Cellular Component	GO:0005737	cytoplasm	Plcb4	IDA		Rat	PMID:9452490|RGD:633576
Cellular Component	GO:0030425	dendrite	Plcb4	IDA		Mouse	PMID:15579147
Cellular Component	GO:0098978	glutamatergic synapse	Plcb4	IDA		Mouse	PMID:11551922
Cellular Component	GO:0098978	glutamatergic synapse	Plcb4	IMP		Mouse	PMID:11551922
Cellular Component	GO:0005634	nucleus	Plcb4	IDA		Mouse	PMID:15579147
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Plcb4	IDA		Mouse	PMID:11551922
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Plcb4	IMP		Mouse	PMID:11551922
Cellular Component	GO:0098794	postsynapse	Plcb4	IDA		Mouse	PMID:15579147
Cellular Component	GO:0098794	postsynapse	Plcb4	IEP		Mouse	PMID:15579147
Cellular Component	GO:0014069	postsynaptic density	Plcb4	IDA		Mouse	PMID:15579147
Cellular Component	GO:0014069	postsynaptic density	Plcb4	IEP		Mouse	PMID:15579147
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Plcb4	IDA		Mouse	PMID:15579147
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Plcb4	IEP		Mouse	PMID:15579147
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Plcb4	IDA		Mouse	PMID:11551922
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Plcb4	IMP		Mouse	PMID:11551922
Biological Process	GO:0043267	negative regulation of potassium ion transport	Plcb4	IMP		Rat	PMID:11050147|RGD:2299873

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern