Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PJA2
  • Mouse genes Pja2
  • Rat genes Pja2
  • Zfish genes pja2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pja2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PJA2	IPI	UniProtKB:Q9Y4C4	Human	PMID:28471450
Molecular Function	GO:0005515	protein binding	PJA2	IPI	UniProtKB:Q96DN5	Human	PMID:33934390
Molecular Function	GO:0005515	protein binding	Pja2	IPI	UniProtKB:P61809	Mouse	MGI:MGI:5582660|PMID:24561619
Molecular Function	GO:0005515	protein binding	Pja2	IPI	UniProtKB:Q8K2H5	Mouse	PMID:11959851
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	PJA2	IMP		Human	PMID:21423175
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	PJA2	IMP		Human	PMID:21423175
Molecular Function	GO:0061630	ubiquitin protein ligase activity	PJA2	IDA		Human	PMID:33934390
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	PJA2	IDA		Human	PMID:21423175
Cellular Component	GO:0034451	centriolar satellite	PJA2	IDA		Human	PMID:33934390
Cellular Component	GO:0005813	centrosome	PJA2	IDA		Human	PMID:33934390
Cellular Component	GO:0005737	cytoplasm	PJA2	IDA		Human	PMID:21423175
Cellular Component	GO:0005737	cytoplasm	PJA2	IDA		Human	PMID:28471450
Cellular Component	GO:0045111	intermediate filament cytoskeleton	PJA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PJA2	IDA		Human	PMID:21423175
Biological Process	GO:0006954	inflammatory response	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0045087	innate immune response	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0007616	long-term memory	Pja2	IMP		Rat	PMID:21423175|RGD:8554183
Biological Process	GO:0046330	positive regulation of JNK cascade	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PJA2	IMP		Human	PMID:33934390
Biological Process	GO:0016567	protein ubiquitination	PJA2	IDA		Human	PMID:21423175
Biological Process	GO:0016567	protein ubiquitination	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0043030	regulation of macrophage activation	PJA2	IMP		Human	PMID:28471450
Biological Process	GO:0010738	regulation of protein kinase A signaling	PJA2	IMP		Human	PMID:21423175
Biological Process	GO:0010738	regulation of protein kinase A signaling	Pja2	IMP		Rat	PMID:21423175|RGD:8554183

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern