Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP
  • Mouse genes Pip
  • Rat genes Pip
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	PIP	IMP		Human	PMID:10713110
Molecular Function	GO:0042802	identical protein binding	PIP	IPI	UniProtKB:P12273	Human	PMID:10713110
Molecular Function	GO:0019864	IgG binding	PIP	IDA		Human	PMID:14638438
Molecular Function	GO:0005515	protein binding	PIP	IPI	UniProtKB:P25311	Human	PMID:18930737
Molecular Function	GO:0005515	protein binding	PIP	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	PIP	IPI	UniProtKB:O14656-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIP	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pip	IPI	PR:Q9WTY4	Mouse	PMID:18696337
Cellular Component	GO:0016324	apical plasma membrane	Pip	IDA		Mouse	PMID:18696337
Cellular Component	GO:0070062	extracellular exosome	PIP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PIP	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PIP	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Pip	IDA		Mouse	PMID:20052012
Cellular Component	GO:0005615	extracellular space	PIP	IDA		Human	PMID:10713110
Cellular Component	GO:0005615	extracellular space	PIP	IDA		Human	PMID:14638438
Cellular Component	GO:0005615	extracellular space	PIP	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	PIP	IDA		Human	PMID:18930737
Cellular Component	GO:0005615	extracellular space	PIP	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	PIP	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	PIP	IDA		Human	PMID:24248522
Cellular Component	GO:0005634	nucleus	PIP	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	PIP	IDA		Human	PMID:22720776
Biological Process	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	PIP	IDA		Human	PMID:24248522
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	PIP	IMP		Human	PMID:10072505
Biological Process	GO:0010628	positive regulation of gene expression	PIP	IDA		Human	PMID:10072505
Biological Process	GO:0006508	proteolysis	PIP	IMP		Human	PMID:10713110
Biological Process	GO:0002682	regulation of immune system process	Pip	IMP	MGI:MGI:5516489	Mouse	PMID:20052012
Biological Process	GO:0001895	retina homeostasis	PIP	HEP		Human	PMID:23580065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern