Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIAS3
  • Mouse genes Pias3
  • Rat genes Pias3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pias3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Pias3	IPI	RGD:2733	Rat	PMID:17486098|RGD:1642482
Molecular Function	GO:0015459	potassium channel regulator activity	Pias3	IDA		Rat	PMID:9565597|RGD:1299426
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q99684	Human	PMID:11060035
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q15911	Human	PMID:14715251
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:P35520	Human	PMID:17087506
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q13330	Human	PMID:21965678
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:O75626	Human	PMID:28842558
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS3	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:P42227	Mouse	MGI:MGI:5294492|PMID:21812053
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:Q99497	Mouse	MGI:MGI:5586804|PMID:11477070
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:Q9QYE3	Mouse	MGI:MGI:3820475|PMID:18681895
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:Q99684	Mouse	MGI:MGI:5142384|PMID:11060035
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:P70338	Mouse	MGI:MGI:5142384|PMID:11060035
Molecular Function	GO:0005515	protein binding	Pias3	IPI	PR:O09106	Mouse	PMID:17442941
Molecular Function	GO:0005515	protein binding	Pias3	IPI	PR:P01101	Mouse	PMID:17442941
Molecular Function	GO:0005515	protein binding	Pias3	IPI	PR:Q08874	Mouse	PMID:17442941
Molecular Function	GO:0005515	protein binding	Pias3	IPI	PR:O88942	Mouse	PMID:17442941
Molecular Function	GO:0005515	protein binding	Pias3	IPI	PR:Q60974	Mouse	PMID:16421255
Molecular Function	GO:0005515	protein binding	Pias3	IPI	RGD:68394	Rat	PMID:10794667|RGD:1581444
Molecular Function	GO:0005515	protein binding	Pias3	IPI	UniProtKB:P42260	Rat	PMID:17486098|RGD:1642482
Molecular Function	GO:0019789	SUMO transferase activity	PIAS3	EXP		Human	PMID:15507434
Molecular Function	GO:0019789	SUMO transferase activity	PIAS3	EXP		Human	PMID:19041634
Molecular Function	GO:0019789	SUMO transferase activity	PIAS3	EXP		Human	PMID:21965678
Molecular Function	GO:0019789	SUMO transferase activity	Pias3	IDA		Mouse	PMID:15767674
Molecular Function	GO:0044325	transmembrane transporter binding	Pias3	IDA		Rat	PMID:9565597|RGD:1299426
Cellular Component	GO:0005737	cytoplasm	Pias3	IDA		Mouse	MGI:MGI:5294492|PMID:21812053
Cellular Component	GO:0030425	dendrite	Pias3	IDA		Rat	PMID:17486098|RGD:1642482
Cellular Component	GO:0005634	nucleus	Pias3	IDA		Mouse	MGI:MGI:5294492|PMID:21812053
Cellular Component	GO:0005634	nucleus	Pias3	IDA		Mouse	PMID:14596924
Cellular Component	GO:0005634	nucleus	Pias3	IDA		Rat	PMID:9565597|RGD:1299426
Cellular Component	GO:0045202	synapse	Pias3	IDA		Rat	PMID:17486098|RGD:1642482
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pias3	IDA		Mouse	PMID:17442941
Biological Process	GO:0010629	negative regulation of gene expression	Pias3	IDA		Mouse	PMID:17442941
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Pias3	IMP		Mouse	PMID:17442941
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Pias3	IDA		Mouse	PMID:17442941
Biological Process	GO:0033234	negative regulation of protein sumoylation	PIAS3	IDA		Human	PMID:24651376
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pias3	IDA		Mouse	PMID:17442941
Biological Process	GO:0010628	positive regulation of gene expression	Pias3	IDA		Rat	PMID:9565597|RGD:1299426
Biological Process	GO:0045838	positive regulation of membrane potential	Pias3	IDA		Rat	PMID:9565597|RGD:1299426
Biological Process	GO:0033235	positive regulation of protein sumoylation	PIAS3	IDA		Human	PMID:17696781
Biological Process	GO:0033235	positive regulation of protein sumoylation	PIAS3	IDA		Human	PMID:21965678
Biological Process	GO:0016925	protein sumoylation	Pias3	IDA		Mouse	PMID:15767674
Biological Process	GO:0009725	response to hormone	Pias3	IEP		Rat	PMID:11133009|RGD:2303125
Biological Process	GO:0071847	TNFSF11-mediated signaling pathway	Pias3	IDA		Mouse	PMID:17442941

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern