Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PELI3
  • Mouse genes Peli3
  • Rat genes Peli3
  • Zfish genes peli3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Peli3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PELI3	IPI	UniProtKB:Q92569	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	Peli3	IPI	PR:Q60855	Mouse	PMID:24113711
Molecular Function	GO:0005515	protein binding	Peli3	IPI	PR:P97433	Mouse	PMID:23892723
Molecular Function	GO:0005515	protein binding	Peli3	IPI	PR:P70196	Mouse	PMID:23042151
Molecular Function	GO:0005515	protein binding	Peli3	IPI	PR:O89110	Mouse	PMID:24113711
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Peli3	IMP		Mouse	PMID:23042151
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Peli3	IDA		Mouse	PMID:23892723
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Peli3	IMP		Mouse	PMID:23892723
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	PELI3	IMP		Human	PMID:24113711
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Peli3	IMP	MGI:MGI:5441750	Mouse	PMID:23950925
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Peli3	IGI	MGI:MGI:108072	Mouse	PMID:23042151
Biological Process	GO:0045751	negative regulation of Toll signaling pathway	Peli3	IGI	MGI:MGI:2156367	Mouse	PMID:23042151
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	PELI3	IMP		Human	PMID:24113711
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	Peli3	IMP	MGI:MGI:5441750	Mouse	PMID:23950925
Biological Process	GO:0032480	negative regulation of type I interferon production	Peli3	IMP	MGI:MGI:5441750	Mouse	PMID:23042151
Biological Process	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Peli3	IMP		Mouse	PMID:23892723
Biological Process	GO:0070534	protein K63-linked ubiquitination	Peli3	IDA		Mouse	PMID:23892723
Biological Process	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Peli3	IMP		Mouse	PMID:23892723

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern