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Peli3 Gene Detail
Summary
  • Symbol
    Peli3
  • Name
    pellino 3
  • Synonyms
    6030441F14Rik, MGC:30417
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924963
    NCBI Gene: 240518
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:4930651-4943127 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924963
protein coding gene Chr19:4929717-4943127 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024682
protein coding gene Chr19:1843240-1858183 (-)
A/J MGP_AJ_G0024648
protein coding gene Chr19:1749368-1761515 (-)
AKR/J MGP_AKRJ_G0024621
protein coding gene Chr19:1795664-1807687 (-)
BALB/cJ MGP_BALBcJ_G0024648
protein coding gene Chr19:1742978-1755184 (-)
C3H/HeJ MGP_C3HHeJ_G0024416
protein coding gene Chr19:1798189-1810183 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025095
protein coding gene Chr19:1899518-1913633 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022525
protein coding gene Chr19:1683803-1697172 (-)
CAST/EiJ MGP_CASTEiJ_G0023888
protein coding gene Chr19:1828315-1840575 (-)
CBA/J MGP_CBAJ_G0024387
protein coding gene Chr19:1975054-1992354 (-)
DBA/2J MGP_DBA2J_G0024515
protein coding gene Chr19:1716163-1743796 (-)
FVB/NJ MGP_FVBNJ_G0024482
protein coding gene Chr19:1738747-1751524 (-)
LP/J MGP_LPJ_G0024601
protein coding gene Chr19:1845277-1859424 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024512
protein coding gene Chr19:1869171-1884393 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025143
protein coding gene Chr19:1793971-1805961 (-)
PWK/PhJ MGP_PWKPhJ_G0023634
protein coding gene Chr19:1767994-1780740 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023439
protein coding gene Chr19:1780702-1793053 (-)
WSB/EiJ MGP_WSBEiJ_G0023950
protein coding gene Chr19:1798228-1822312 (-)



Homology
more
  • Human Ortholog
    PELI3, pellino E3 ubiquitin protein ligase family member 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PELI3, pellino E3 ubiquitin protein ligase family member 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 246330
    neXtProt AC: NX_Q8N2H9
    UniProt: Q8N2H9

  • Chr Location
    11q13.2; chr11:66466327-66477337 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display decreased susceptibility to viral infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024901 Ensembl Gene Model | MGI Sequence Detail 12477 C57BL/6J ±  kb
transcript ENSMUST00000025834 Ensembl | MGI Sequence Detail 1971 Not Applicable  
polypeptide ENSMUSP00000025834 Ensembl | MGI Sequence Detail 445 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 1
Other
Accession IDs
less
MGI:2679258
References
more
  • Summaries
    All 33
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:257996 Yang S, et al., The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance. Immunity. 2014 Dec 18;41(6):973-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory