Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PEAK1
  • Mouse genes Peak1
  • Rat genes Peak1
  • Zfish genes peak1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Peak1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	PEAK1	IDA		Human	PMID:29212708
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	PEAK1	IDA		Human	PMID:20534451
Molecular Function	GO:0005515	protein binding	PEAK1	IPI	UniProtKB:P46108	Human	PMID:20534451
Molecular Function	GO:0005515	protein binding	PEAK1	IPI	UniProtKB:P56945	Human	PMID:20534451
Molecular Function	GO:0005515	protein binding	PEAK1	IPI	UniProtKB:P29353	Human	PMID:23846654
Molecular Function	GO:0005515	protein binding	PEAK1	IPI	UniProtKB:Q86YV5	Human	PMID:29079850
Cellular Component	GO:0015629	actin cytoskeleton	PEAK1	IDA		Human	PMID:20534451
Cellular Component	GO:0015629	actin cytoskeleton	PEAK1	IDA		Human	PMID:23105102
Cellular Component	GO:0015629	actin cytoskeleton	Peak1	IDA		Mouse	MGI:MGI:5009355|PMID:20534451
Cellular Component	GO:0005925	focal adhesion	PEAK1	IDA		Human	PMID:20534451
Cellular Component	GO:0005925	focal adhesion	PEAK1	IDA		Human	PMID:23105102
Cellular Component	GO:0005925	focal adhesion	Peak1	IDA		Mouse	MGI:MGI:5009355|PMID:20534451
Biological Process	GO:0001525	angiogenesis	peak1	IMP	ZFIN:ZDB-MRPHLNO-180918-3	Zfish	PMID:29872538
Biological Process	GO:0016477	cell migration	PEAK1	IDA		Human	PMID:20534451
Biological Process	GO:0016477	cell migration	PEAK1	IMP		Human	PMID:23105102
Biological Process	GO:0048041	focal adhesion assembly	PEAK1	IMP		Human	PMID:23105102
Biological Process	GO:0046777	protein autophosphorylation	PEAK1	IDA		Human	PMID:20534451
Biological Process	GO:0043535	regulation of blood vessel endothelial cell migration	peak1	IMP	ZFIN:ZDB-MRPHLNO-180918-3	Zfish	PMID:29872538
Biological Process	GO:0051893	regulation of focal adhesion assembly	PEAK1	IDA		Human	PMID:23105102
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	PEAK1	IDA		Human	PMID:20534451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern