Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDE1C
  • Mouse genes Pde1c
  • Rat genes Pde1c
  • Zfish genes pde1ca,pde1cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pde1c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	PDE1C	IDA		Human	PMID:29860631
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	Pde1c	IDA		Mouse	MGI:MGI:83312|PMID:8810348
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	PDE1C	IDA		Human	PMID:29860631
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	Pde1c	IDA		Mouse	MGI:MGI:83312|PMID:8810348
Molecular Function	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	Pde1c	IDA		Rat	PMID:7568196|RGD:68318
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	PDE1C	IDA		Human	PMID:8557689
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	Pde1c	IDA		Rat	PMID:7568196|RGD:68318
Molecular Function	GO:0030552	cAMP binding	Pde1c	IDA		Rat	PMID:7568196|RGD:68318
Cellular Component	GO:0005929	cilium	Pde1c	IDA		Mouse	PMID:19305400
Cellular Component	GO:0005764	lysosome	Pde1c	IDA		Mouse	MGI:MGI:6730552|PMID:29860631
Cellular Component	GO:0043025	neuronal cell body	Pde1c	IDA		Rat	PMID:16881052|RGD:2312522
Biological Process	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	Pde1c	IMP		Rat	PMID:18706893|RGD:2302857
Biological Process	GO:0051592	response to calcium ion	Pde1c	IDA		Rat	PMID:7568196|RGD:68318
Biological Process	GO:0007608	sensory perception of smell	Pde1c	IGI	MGI:MGI:99558	Mouse	PMID:19305400
Biological Process	GO:0007608	sensory perception of smell	Pde1c	IMP	MGI:MGI:3851438	Mouse	PMID:19305400
Biological Process	GO:0007608	sensory perception of smell	Pde1c	IEP		Rat	PMID:7568196|RGD:68318

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern