Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCP4
  • Mouse genes Pcp4
  • Rat genes Pcp4
  • Zfish genes pcp4a,pcp4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	PCP4	IDA		Human	PMID:23204517
Molecular Function	GO:0005516	calmodulin binding	PCP4	IPI	UniProtKB:P62149	Human	PMID:19106096
Molecular Function	GO:0005516	calmodulin binding	PCP4	IDA		Human	PMID:23204517
Molecular Function	GO:0005516	calmodulin binding	Pcp4	IDA		Mouse	PMID:22458599
Molecular Function	GO:0005516	calmodulin binding	Pcp4	IDA		Rat	PMID:10751438|RGD:1579763
Molecular Function	GO:0005515	protein binding	PCP4	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PCP4	IPI	UniProtKB:Q8TD86	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	Pcp4	IDA		Rat	PMID:22020791|RGD:9850156
Cellular Component	GO:0030424	axon	Pcp4	IDA		Rat	PMID:10556647|RGD:9850249
Cellular Component	GO:0005737	cytoplasm	Pcp4	IDA		Rat	PMID:10556647|RGD:9850249
Cellular Component	GO:0005829	cytosol	PCP4	HDA		Human	PMID:16780588
Cellular Component	GO:0005883	neurofilament	Pcp4	IDA		Rat	PMID:10556647|RGD:9850249
Cellular Component	GO:0043005	neuron projection	Pcp4	IDA		Rat	PMID:10556647|RGD:9850249
Cellular Component	GO:0005634	nucleus	PCP4	HDA		Human	PMID:16780588
Cellular Component	GO:0032991	protein-containing complex	PCP4	IDA		Human	PMID:19106096
Biological Process	GO:0099004	calmodulin dependent kinase signaling pathway	PCP4	IMP		Human	PMID:21491429
Biological Process	GO:1905232	cellular response to L-glutamate	Pcp4	IEP		Rat	PMID:18502590|RGD:9850275
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pcp4	IDA		Rat	PMID:11117479|RGD:1579764
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pcp4	IMP		Rat	PMID:21671256|RGD:9850149
Biological Process	GO:0006469	negative regulation of protein kinase activity	Pcp4	IDA		Rat	PMID:10751438|RGD:1579763
Biological Process	GO:0001649	osteoblast differentiation	Pcp4	IEP		Rat	PMID:18008138|RGD:9850248
Biological Process	GO:0033603	positive regulation of dopamine secretion	Pcp4	IMP		Rat	PMID:21671256|RGD:9850149
Biological Process	GO:0045666	positive regulation of neuron differentiation	PCP4	IMP		Human	PMID:21491429
Biological Process	GO:0010976	positive regulation of neuron projection development	Pcp4	IMP		Rat	PMID:21671256|RGD:9850149
Biological Process	GO:0006970	response to osmotic stress	Pcp4	IEP		Rat	PMID:11003989|RGD:9850274

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern