| GO term: | neurofilament |
| Synonym: | type IV intermediate filament |
| GO id: | GO:0005883 |
| Definition: | A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. |
| Number of paths to term: | 40 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partcell projectioncell projection partaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcellcell partcell projectionneuron projectionaxonaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcellcell partcell projection partaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellularintracellular partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcellcell partintracellular partintracellular organelleintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partintracellular partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcellcell partneuron partneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcellcell partneuron partneuron projectionaxonaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcell partcell projectioncell projection partaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcell partcell projectionneuron projectionaxonaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcell partcell projection partaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcell partintracellularintracellular partintracellular organelleintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellularintracellular partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcell partintracellular partintracellular organelleintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partintracellular partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentcell partneuron partneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentcell partneuron partneuron projectionaxonaxon partaxolemmaaxon collateral +axon hillockaxon initial segmentaxon microtubule bundleaxon terminus +axonal growth coneaxonal spineinternode region of axonjuxtaparanode region of axonmain axon +neurofilament [GO:0005883] (8 genes, 9 annotations)node of Ranvierparallel fiberparanode region of axonpericellular basketpinceau fibersubsynaptic reticulumterminal bouton +varicositycellular_componentmacromolecular complexprotein complexintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentorganelleintracellular organelleintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellecytoskeletonintermediate filament cytoskeletonneurofilament cytoskeletonneurofilament [GO:0005883] (8 genes, 9 annotations)cellular_componentorganelleorganelle partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentcellular_componentorganelle partintracellular organelle partcytoskeletal partintermediate filamentglial filamentkeratin filamentlamin filamentneurofilament [GO:0005883] (8 genes, 9 annotations)type III intermediate filamentMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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