Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PBX3
  • Mouse genes Pbx3
  • Rat genes Pbx3
  • Zfish genes pbx3a,pbx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pbx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pbx3	IDA		Mouse	MGI:MGI:3505657|PMID:15466398
Molecular Function	GO:0005515	protein binding	Pbx3	IPI	UniProtKB:P09079	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Pbx3	IPI	PR:O70477	Mouse	PMID:10381567
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pbx3	IDA		Mouse	MGI:MGI:3505657|PMID:15466398
Molecular Function	GO:0043565	sequence-specific DNA binding	Pbx3	IDA		Mouse	PMID:16847320
Cellular Component	GO:0005634	nucleus	Pbx3	IDA		Mouse	PMID:15466398
Cellular Component	GO:0005634	nucleus	Pbx3	IDA		Mouse	PMID:18155191
Cellular Component	GO:0005634	nucleus	Pbx3	IDA		Mouse	PMID:10842069
Cellular Component	GO:0005667	transcription regulator complex	Pbx3	IDA		Mouse	PMID:15466398
Cellular Component	GO:0005667	transcription regulator complex	Pbx3	IDA		Mouse	PMID:10381567
Biological Process	GO:0008344	adult locomotory behavior	Pbx3	IMP	MGI:MGI:3773271,MGI:MGI:3773272	Mouse	PMID:18155191
Biological Process	GO:0021516	dorsal spinal cord development	Pbx3	IMP	MGI:MGI:3773271,MGI:MGI:3773272	Mouse	PMID:18155191
Biological Process	GO:0048666	neuron development	Pbx3	IMP	MGI:MGI:3773271,MGI:MGI:3773272	Mouse	PMID:18155191
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pbx3	IDA		Mouse	MGI:MGI:3505657|PMID:15466398
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	Pbx3	IMP	MGI:MGI:3510441	Mouse	PMID:15527896
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Pbx3	IMP	MGI:MGI:3510441	Mouse	PMID:15466398

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern