Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PANX2
  • Mouse genes Panx2
  • Rat genes Panx2
  • Zfish genes panx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Panx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Panx2	IMP		Rat	PMID:14597722|RGD:1299639
Molecular Function	GO:0044877	protein-containing complex binding	Panx2	IMP		Rat	PMID:14597722|RGD:1299639
Cellular Component	GO:0005737	cytoplasm	Panx2	IDA		Mouse	PMID:20086016
Cellular Component	GO:0031410	cytoplasmic vesicle	panx2	IDA		Zfish	PMID:22922822
Cellular Component	GO:0005886	plasma membrane	PANX2	IDA		Human	GO_REF:0000052
Biological Process	GO:0007267	cell-cell signaling	Panx2	IMP		Rat	PMID:14597722|RGD:1299639
Biological Process	GO:0002931	response to ischemia	Panx2	IGI	MGI:MGI:1860055	Mouse	PMID:22147915

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern