Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pals1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PALS1
- Mouse genes Pals1
- Rat genes Pals1
- Zfish genes pals1a,pals1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pals1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	PALS1	IPI	UniProtKB:Q8N3R9	Human	PMID:15914641
Molecular Function	GO:0042802	identical protein binding	PALS1	IPI	UniProtKB:Q8N3R9	Human	PMID:34103506
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P82279	Human	PMID:11927608
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q8NI35	Human	PMID:11927608
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P82279	Human	PMID:15914641
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q96JB8	Human	PMID:15914641
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q13368	Human	PMID:16519681
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q00013	Human	PMID:17584769
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P82279	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P82279\|UniProtKB:Q9HCM4	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9HCM4	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q8NI35	Human	PMID:21481793
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O14910	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q8NI35	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9NUP9	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O14910	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O14910	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:A0A286YEY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O14910	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O95954	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9HAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9NUP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9NY99-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9Y2H0-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P02766	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P0DTC4	Human	PMID:32822073
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P59637	Human	PMID:32822073
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P0DTC4	Human	PMID:33758649
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P59637	Human	PMID:33758649
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P82279	Human	PMID:33758649
Molecular Function	GO:0005515	protein binding	PALS1	IPI	UniProtKB:P0DTC4	Human	PMID:34103506
Molecular Function	GO:0005515	protein binding	Pals1	IPI	UniProtKB:Q9GZV5	Mouse	MGI:MGI:4939579\|PMID:21145499
Molecular Function	GO:0005515	protein binding	Pals1	IPI	UniProtKB:Q63ZW7\|UniProtKB:Q80YA8	Mouse	MGI:MGI:4454735\|PMID:20399730
Molecular Function	GO:0005515	protein binding	Pals1	IPI	UniProtKB:O88910	Mouse	MGI:MGI:7434896\|PMID:16519681
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q9CZN4	Mouse	PMID:24498314
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q8K371	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q8VBX6	Mouse	PMID:19506035
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q8VBX6	Mouse	PMID:15316081
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q8VHG2	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Pals1	IPI	PR:Q9D4H4	Mouse	PMID:18824598
Molecular Function	GO:0019904	protein domain specific binding	PALS1	IPI	UniProtKB:Q5T2T1	Human	PMID:17332497
Molecular Function	GO:0019904	protein domain specific binding	PALS1	IPI	UniProtKB:Q9BUF7	Human	PMID:17332497
Cellular Component	GO:0005912	adherens junction	PALS1	IDA		Human	PMID:15914641
Cellular Component	GO:0005912	adherens junction	Pals1	IDA		Mouse	MGI:MGI:4939579\|PMID:21145499
Cellular Component	GO:0043296	apical junction complex	pals1a	IDA		Zfish	PMID:18628301
Cellular Component	GO:0045177	apical part of cell	Pals1	IDA		Mouse	PMID:25636444
Cellular Component	GO:0005737	cytoplasm	PALS1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0070062	extracellular exosome	PALS1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PALS1	HDA		Human	PMID:23533145
Cellular Component	GO:0043219	lateral loop	Pals1	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Cellular Component	GO:0035749	myelin sheath adaxonal region	Pals1	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Cellular Component	GO:0005634	nucleus	pals1a	IDA		Zfish	PMID:18058913
Cellular Component	GO:0001917	photoreceptor inner segment	pals1a	IDA		Zfish	PMID:16530752
Cellular Component	GO:0005886	plasma membrane	Pals1	IDA		Mouse	MGI:MGI:6219868\|PMID:26404741
Cellular Component	GO:0005886	plasma membrane	Pals1	IDA		Mouse	PMID:10753959
Cellular Component	GO:0005886	plasma membrane	pals1a	IDA		Zfish	PMID:18058913
Cellular Component	GO:0032991	protein-containing complex	PALS1	IDA		Human	PMID:15914641
Cellular Component	GO:0032991	protein-containing complex	Pals1	IDA		Rat	PMID:18621709\|RGD:5131983
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Pals1	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Biological Process	GO:0045176	apical protein localization	pals1a	IGI	ZFIN:ZDB-GENO-980202-307	Zfish	PMID:18628301
Biological Process	GO:0045176	apical protein localization	pals1a	IGI	ZFIN:ZDB-GENE-010319-35,ZFIN:ZDB-GENO-980202-452	Zfish	PMID:18628301
Biological Process	GO:0007420	brain development	pals1a	IMP	ZFIN:ZDB-GENO-070130-4	Zfish	PMID:19051268
Biological Process	GO:0007420	brain development	pals1a	IMP	ZFIN:ZDB-GENO-050317-4	Zfish	PMID:15788456
Biological Process	GO:0007420	brain development	pals1a	IMP	ZFIN:ZDB-GENO-050317-4	Zfish	PMID:15593329
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	pals1a	IMP	ZFIN:ZDB-MRPHLNO-081209-3	Zfish	PMID:18628301
Biological Process	GO:0098609	cell-cell adhesion	pals1a	IMP	ZFIN:ZDB-GENO-980202-279	Zfish	PMID:16530752
Biological Process	GO:0021954	central nervous system neuron development	Pals1	IMP		Mouse	MGI:MGI:4454735\|PMID:20399730
Biological Process	GO:0021987	cerebral cortex development	Pals1	IMP		Mouse	MGI:MGI:4454735\|PMID:20399730
Biological Process	GO:0021744	dorsal motor nucleus of vagus nerve development	pals1a	IMP	ZFIN:ZDB-MRPHLNO-110223-3	Zfish	PMID:21262462
Biological Process	GO:0035050	embryonic heart tube development	pals1a	IMP	ZFIN:ZDB-GENO-980202-452	Zfish	PMID:16319113
Biological Process	GO:0035050	embryonic heart tube development	pals1a	IMP	ZFIN:ZDB-GENO-060118-4	Zfish	PMID:16319113
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-081218-2	Zfish	PMID:19074041
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-110823-10	Zfish	PMID:20362667
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-090619-3	Zfish	PMID:19074041
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-080709-10	Zfish	PMID:18058913
Biological Process	GO:0035088	establishment or maintenance of apical/basal cell polarity	pals1a	IMP	ZFIN:ZDB-GENO-080709-10	Zfish	PMID:18628301
Biological Process	GO:0035088	establishment or maintenance of apical/basal cell polarity	pals1a	IMP	ZFIN:ZDB-GENO-980202-452	Zfish	PMID:17227894
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	pals1a	IMP	ZFIN:ZDB-GENO-081218-2	Zfish	PMID:20080584
Biological Process	GO:0016332	establishment or maintenance of polarity of embryonic epithelium	pals1a	IMP	ZFIN:ZDB-MRPHLNO-060118-2	Zfish	PMID:16319113
Biological Process	GO:0010467	gene expression	Pals1	IMP		Mouse	PMID:16885194
Biological Process	GO:0048699	generation of neurons	pals1a	IMP	ZFIN:ZDB-GENO-110823-10	Zfish	PMID:20362667
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	pals1a	IMP	ZFIN:ZDB-GENO-080709-10	Zfish	PMID:18058913
Biological Process	GO:0008078	mesodermal cell migration	pals1a	IMP	ZFIN:ZDB-GENO-980202-452	Zfish	PMID:14576439
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	PALS1	IMP		Human	PMID:23201090
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	pals1a	IMP	ZFIN:ZDB-GENO-080709-10	Zfish	PMID:18058913
Biological Process	GO:0032288	myelin assembly	Pals1	IMP		Rat	PMID:20237282\|RGD:8554674
Biological Process	GO:0001841	neural tube formation	pals1a	IMP	ZFIN:ZDB-GENO-081218-2	Zfish	PMID:18817769
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	Pals1	IMP		Mouse	MGI:MGI:4441217\|PMID:20237282
Biological Process	GO:0007009	plasma membrane organization	Pals1	IMP		Mouse	PMID:19506035
Biological Process	GO:0008104	protein localization	Pals1	IMP		Mouse	PMID:16885194
Biological Process	GO:0035750	protein localization to myelin sheath abaxonal region	Pals1	IMP		Mouse	MGI:MGI:4441217\|PMID:20237282
Biological Process	GO:0072659	protein localization to plasma membrane	Pals1	IMP		Rat	PMID:20237282\|RGD:8554674
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Pals1	IMP		Mouse	MGI:MGI:4939579\|PMID:21145499
Biological Process	GO:0060041	retina development in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-980202-279	Zfish	PMID:16530752
Biological Process	GO:0060041	retina development in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-040924-4	Zfish	PMID:15716491
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-980202-452	Zfish	PMID:18628301
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	pals1a	IMP	ZFIN:ZDB-GENO-080709-10	Zfish	PMID:18628301
Biological Process	GO:0021591	ventricular system development	pals1a	IMP	ZFIN:ZDB-GENO-980202-279	Zfish	PMID:9007238

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.