Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pacsin1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PACSIN1
- Mouse genes Pacsin1
- Rat genes Pacsin1
- Zfish genes pacsin1a,pacsin1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pacsin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	Pacsin1	IDA		Mouse	PMID:11082044
Molecular Function	GO:0042802	identical protein binding	Pacsin1	IPI	UniProtKB:Q61644	Mouse	MGI:MGI:4454229\|PMID:20404169
Molecular Function	GO:0005543	phospholipid binding	PACSIN1	IDA		Human	PMID:19549836
Molecular Function	GO:0005543	phospholipid binding	Pacsin1	IDA		Mouse	MGI:MGI:4454229\|PMID:20404169
Molecular Function	GO:0005543	phospholipid binding	Pacsin1	IDA		Rat	PMID:22355135\|RGD:8554204
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UNF0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:P48023	Human	PMID:16318909
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:P42858	Human	PMID:17161366
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:O75128	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UNF0	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9NUX5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:O14672	Human	PMID:25036101
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UKS6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UNF0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UKS6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:O75128	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UNF0	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UKS6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UKS6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UNF0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:O00746	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q8IYM2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q8TAB7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PACSIN1	IPI	UniProtKB:Q9UMY4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:P19332-5	Mouse	MGI:MGI:5516178\|PMID:23035120
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:P10637	Mouse	MGI:MGI:5516178\|PMID:23035120
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	PR:Q99JB8	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	PR:Q9WVE8	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	PR:Q91YD9	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	PR:Q61644	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	RGD:71096	Rat	PMID:16648848\|RGD:13504740
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:Q9NZQ3	Rat	PMID:16999739\|RGD:8553470
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:P21575	Rat	PMID:17437541\|RGD:8554440
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:Q5NBX1	Rat	PMID:17956734\|RGD:8554195
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:D3ZUI5	Rat	PMID:21725280\|RGD:8554579
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:Q5NBX1	Rat	PMID:21725280\|RGD:8554579
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:D3ZUI5	Rat	PMID:26334624\|RGD:11068797
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	UniProtKB:Q5NBX1-1	Rat	PMID:26334624\|RGD:11068797
Molecular Function	GO:0005515	protein binding	Pacsin1	IPI	RGD:69434\|RGD:71096\|RGD:3797\|RGD:735144	Rat	PMID:9950691\|RGD:69919
Cellular Component	GO:0043679	axon terminus	Pacsin1	IDA		Rat	PMID:22355135\|RGD:8554204
Cellular Component	GO:0030137	COPI-coated vesicle	Pacsin1	IDA		Mouse	PMID:9746365
Cellular Component	GO:0005737	cytoplasm	PACSIN1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	Pacsin1	IDA		Mouse	MGI:MGI:4454229\|PMID:20404169
Cellular Component	GO:0005737	cytoplasm	Pacsin1	IDA		Mouse	PMID:11082044
Cellular Component	GO:0098978	glutamatergic synapse	Pacsin1	IDA		Rat	PMID:16617342\|RGD:13702454
Cellular Component	GO:0098978	glutamatergic synapse	Pacsin1	IMP		Rat	PMID:16617342\|RGD:13702454
Cellular Component	GO:0098978	glutamatergic synapse	Pacsin1	IDA		Rat	PMID:23918399\|RGD:13702399
Cellular Component	GO:0098978	glutamatergic synapse	Pacsin1	IMP		Rat	PMID:23918399\|RGD:13702399
Cellular Component	GO:0043209	myelin sheath	Pacsin1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Pacsin1	IDA		Rat	PMID:21725280\|RGD:8554579
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Pacsin1	IDA		Mouse	PMID:23785143
Cellular Component	GO:0005886	plasma membrane	Pacsin1	IDA		Rat	PMID:21725280\|RGD:8554579
Cellular Component	GO:0098839	postsynaptic density membrane	Pacsin1	IDA		Rat	PMID:16617342\|RGD:13702454
Cellular Component	GO:0098793	presynapse	Pacsin1	IDA		Mouse	MGI:MGI:5304995\|PMID:21926968
Cellular Component	GO:0098833	presynaptic endocytic zone	Pacsin1	IDA		Mouse	PMID:23785143
Cellular Component	GO:0032587	ruffle membrane	Pacsin1	IDA		Mouse	MGI:MGI:4454229\|PMID:20404169
Cellular Component	GO:0045202	synapse	Pacsin1	IDA		Mouse	MGI:MGI:5304995\|PMID:21926968
Cellular Component	GO:0045202	synapse	Pacsin1	IDA		Rat	PMID:21725280\|RGD:8554579
Cellular Component	GO:0043195	terminal bouton	Pacsin1	HDA		Rat	PMID:24876496\|RGD:10047219
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	pacsin1b	IMP	ZFIN:ZDB-MRPHLNO-130522-3,ZFIN:ZDB-MRPHLNO-130531-3	Zfish	PMID:23203810
Biological Process	GO:0060271	cilium assembly	pacsin1b	IMP	ZFIN:ZDB-CRISPR-190703-3,ZFIN:ZDB-CRISPR-190703-2	Zfish	PMID:30683896
Biological Process	GO:0060271	cilium assembly	pacsin1b	IGI	ZFIN:ZDB-GENE-040426-2596	Zfish	PMID:30683896
Biological Process	GO:0007010	cytoskeleton organization	Pacsin1	IDA		Rat	PMID:9950691\|RGD:69919
Biological Process	GO:0045806	negative regulation of endocytosis	Pacsin1	IDA		Mouse	PMID:11082044
Biological Process	GO:0048812	neuron projection morphogenesis	Pacsin1	IMP		Rat	PMID:22355135\|RGD:8554204
Biological Process	GO:0097320	plasma membrane tubulation	PACSIN1	IDA		Human	PMID:19549836
Biological Process	GO:0097320	plasma membrane tubulation	Pacsin1	IMP		Mouse	MGI:MGI:4454229\|PMID:20404169
Biological Process	GO:0097320	plasma membrane tubulation	Pacsin1	IMP		Rat	PMID:22355135\|RGD:8554204
Biological Process	GO:1900006	positive regulation of dendrite development	Pacsin1	IDA		Rat	PMID:21725280\|RGD:8554579
Biological Process	GO:0072657	protein localization to membrane	Pacsin1	IMP		Mouse	MGI:MGI:5304995\|PMID:21926968
Biological Process	GO:0072659	protein localization to plasma membrane	Pacsin1	IDA		Rat	PMID:21725280\|RGD:8554579
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pacsin1	IDA		Rat	PMID:16617342\|RGD:13702454
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pacsin1	IMP		Rat	PMID:16617342\|RGD:13702454
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pacsin1	IDA		Rat	PMID:23918399\|RGD:13702399
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pacsin1	IMP		Rat	PMID:23918399\|RGD:13702399
Biological Process	GO:0048488	synaptic vesicle endocytosis	Pacsin1	IDA		Mouse	PMID:21926968
Biological Process	GO:0048488	synaptic vesicle endocytosis	Pacsin1	IMP		Mouse	PMID:21926968

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.