Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ONECUT3
  • Mouse genes Onecut3
  • Rat genes
  • Zfish genes onecut3a,onecut3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Onecut3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Onecut3	IDA		Mouse	MGI:MGI:2178162|PMID:11944891
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Onecut3	IDA		Mouse	PMID:11944891
Molecular Function	GO:0005515	protein binding	ONECUT3	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ONECUT3	IPI	UniProtKB:Q99828	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ONECUT3	IPI	UniProtKB:Q9H0C1	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Onecut3	IDA		Mouse	MGI:MGI:2178162|PMID:11944891
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ONECUT3	IDA		Human	PMID:28473536
Cellular Component	GO:0005667	transcription regulator complex	Onecut3	IDA		Mouse	PMID:11944891
Biological Process	GO:0006351	DNA-templated transcription	Onecut3	IDA		Mouse	MGI:MGI:2178162|PMID:11944891
Biological Process	GO:0001889	liver development	onecut3a	IMP	ZFIN:ZDB-MRPHLNO-080327-2	Zfish	PMID:18095340
Biological Process	GO:0001889	liver development	onecut3a	IMP	ZFIN:ZDB-MRPHLNO-080327-1	Zfish	PMID:18095340
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Onecut3	IDA		Mouse	MGI:MGI:2178162|PMID:11944891
Biological Process	GO:0006355	regulation of DNA-templated transcription	Onecut3	IDA		Mouse	MGI:MGI:2178162|PMID:11944891
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Onecut3	IDA		Mouse	PMID:11944891

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern