Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NRAS
  • Mouse genes Nras
  • Rat genes Nras
  • Zfish genes nras
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nras

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003924	GTPase activity	NRAS	IDA		Human	PMID:30712867
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:18641128
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:20080631
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:21478863
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P15056	Human	PMID:21478863
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P28028	Human	PMID:21478863
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:Q99N57	Human	PMID:21478863
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:Q13671	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:30194290
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P15056	Human	PMID:30194290
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P49842	Human	PMID:30712867
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P04049	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P52306-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:Q13671	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:Q3MIN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:Q96II5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P15056	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	NRAS	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nras	IPI	UniProtKB:O08773	Rat	PMID:19319189|RGD:8554645
Molecular Function	GO:0044877	protein-containing complex binding	NRAS	IDA		Human	PMID:23209302
Cellular Component	GO:0070062	extracellular exosome	NRAS	HDA		Human	PMID:20458337
Cellular Component	GO:0005794	Golgi apparatus	NRAS	IDA		Human	PMID:21968647
Cellular Component	GO:0016020	membrane	NRAS	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Nras	IDA		Mouse	PMID:10085069
Biological Process	GO:0042832	defense response to protozoan	Nras	IMP	MGI:MGI:2385944	Mouse	PMID:21444916
Biological Process	GO:0045445	myoblast differentiation	Nras	IEP		Rat	PMID:2425941|RGD:151667421
Biological Process	GO:0048642	negative regulation of skeletal muscle tissue development	Nras	IGI	MGI:MGI:2676890	Mouse	PMID:20534588
Biological Process	GO:0048642	negative regulation of skeletal muscle tissue development	Nras	IDA		Mouse	PMID:20534588
Biological Process	GO:0045766	positive regulation of angiogenesis	Nras	IMP		Mouse	MGI:MGI:5514117|PMID:23619365
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	NRAS	IMP		Human	PMID:23619365
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Nras	IMP		Mouse	PMID:23871832
Biological Process	GO:0032729	positive regulation of type II interferon production	Nras	IMP	MGI:MGI:2385944	Mouse	PMID:21444916
Biological Process	GO:0007265	Ras protein signal transduction	NRAS	IDA		Human	PMID:30712867
Biological Process	GO:0010468	regulation of gene expression	Nras	IMP		Mouse	PMID:23871832
Biological Process	GO:0001932	regulation of protein phosphorylation	Nras	IMP		Mouse	PMID:23871832
Biological Process	GO:0050852	T cell receptor signaling pathway	Nras	IMP	MGI:MGI:2385944	Mouse	PMID:21444916

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern