Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR6A1
  • Mouse genes Nr6a1
  • Rat genes Nr6a1
  • Zfish genes nr6a1a,nr6a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr6a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr6a1	IDA		Mouse	MGI:MGI:5572906|PMID:9099702
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr6a1	IMP		Mouse	MGI:MGI:5572906|PMID:9099702
Molecular Function	GO:0005515	protein binding	Nr6a1	IPI	UniProtKB:Q96RL1	Mouse	MGI:MGI:3693399|PMID:12080054
Molecular Function	GO:0005515	protein binding	Nr6a1	IPI	PR:Q9WU42	Mouse	PMID:11702949
Molecular Function	GO:0042803	protein homodimerization activity	Nr6a1	IDA		Mouse	MGI:MGI:3715068|PMID:9025060
Molecular Function	GO:0042803	protein homodimerization activity	Nr6a1	IDA		Mouse	MGI:MGI:69378|PMID:7854358
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr6a1	IMP		Mouse	MGI:MGI:5572906|PMID:9099702
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr6a1	IDA		Mouse	PMID:16166633
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr6a1	IDA		Mouse	PMID:11702949
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr6a1	IDA		Mouse	MGI:MGI:69378|PMID:7854358
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr6a1	IDA		Mouse	MGI:MGI:3715068|PMID:9025060
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR6A1	IDA		Human	PMID:28473536
Cellular Component	GO:0005667	transcription regulator complex	Nr6a1	IDA		Mouse	PMID:16166633
Biological Process	GO:0007276	gamete generation	Nr6a1	IEP		Mouse	MGI:MGI:70520|PMID:7835709
Biological Process	GO:0007276	gamete generation	Nr6a1	IEP		Mouse	MGI:MGI:69378|PMID:7854358
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr6a1	IDA		Mouse	PMID:11702949
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr6a1	IMP	MGI:MGI:2448158	Mouse	PMID:12381721
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr6a1	IDA		Mouse	PMID:16166633
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr6a1	IMP	MGI:MGI:2385846	Mouse	PMID:12381721
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr6a1	IDA		Mouse	MGI:MGI:5572906|PMID:9099702

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern