Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR1I3
  • Mouse genes Nr1i3
  • Rat genes Nr1i3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr1i3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Nr1i3	IDA		Mouse	PMID:11891224
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NR1I3	IDA		Human	PMID:11114890
Molecular Function	GO:0004879	nuclear receptor activity	NR1I3	IDA		Human	PMID:9783588
Molecular Function	GO:0005515	protein binding	NR1I3	IPI	UniProtKB:P01100	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	UniProtKB:Q07139	Mouse	MGI:MGI:3762312|PMID:17904126
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	UniProtKB:P97784|UniProtKB:Q9R194	Mouse	MGI:MGI:5913754|PMID:28751364
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:P62715	Mouse	PMID:12885400
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:P70365	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:Q60974	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:P63330	Mouse	PMID:12885400
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:Q00286	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	MGI:MGI:1926334	Mouse	PMID:12885400
Molecular Function	GO:0005515	protein binding	Nr1i3	IPI	PR:P07901	Mouse	PMID:12885400
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NR1I3	IDA		Human	PMID:11114890
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR1I3	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Nr1i3	IDA		Mouse	MGI:MGI:3762312|PMID:17904126
Cellular Component	GO:0005737	cytoplasm	Nr1i3	IDA		Rat	PMID:19920082|RGD:9835392
Cellular Component	GO:0005829	cytosol	Nr1i3	IDA		Mouse	PMID:12885400
Cellular Component	GO:0005654	nucleoplasm	NR1I3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nr1i3	IDA		Mouse	MGI:MGI:3762312|PMID:17904126
Cellular Component	GO:0005634	nucleus	Nr1i3	IDA		Mouse	PMID:12885400
Cellular Component	GO:0005634	nucleus	Nr1i3	IDA		Rat	PMID:19920082|RGD:9835392
Cellular Component	GO:0005634	nucleus	Nr1i3	IDA		Rat	PMID:29204052|RGD:13782189
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr1i3	IDA		Mouse	PMID:11891224
Biological Process	GO:0001649	osteoblast differentiation	Nr1i3	IEP		Rat	PMID:19702932|RGD:9835391
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR1I3	IDA		Human	PMID:11114890
Biological Process	GO:0006355	regulation of DNA-templated transcription	Nr1i3	IDA		Mouse	PMID:11891224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern