Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NMUR2
  • Mouse genes Nmur2
  • Rat genes Nmur2
  • Zfish genes nmur1b,nmur3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nmur2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	NMUR2	IDA		Human	PMID:10899166
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	NMUR2	IDA		Human	PMID:10899166
Molecular Function	GO:0042924	neuromedin U binding	NMUR2	IDA		Human	PMID:10894543
Molecular Function	GO:0042924	neuromedin U binding	NMUR2	IDA		Human	PMID:10899166
Molecular Function	GO:0001607	neuromedin U receptor activity	NMUR2	IDA		Human	PMID:10887190
Molecular Function	GO:0001607	neuromedin U receptor activity	NMUR2	IDA		Human	PMID:10894543
Molecular Function	GO:0008188	neuropeptide receptor activity	Nmur2	IPI	UniProtKB:Q5H8A2	Mouse	PMID:15635449
Molecular Function	GO:0008188	neuropeptide receptor activity	Nmur2	IPI	UniProtKB:P12760	Mouse	PMID:15635449
Molecular Function	GO:0008188	neuropeptide receptor activity	Nmur2	IDA		Rat	PMID:10894543|RGD:632965
Molecular Function	GO:0005515	protein binding	NMUR2	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NMUR2	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NMUR2	IPI	UniProtKB:Q6UY14-3	Human	PMID:25416956
Cellular Component	GO:0016020	membrane	NMUR2	IDA		Human	PMID:10899166
Cellular Component	GO:0005886	plasma membrane	NMUR2	IDA		Human	GO_REF:0000052
Biological Process	GO:0050482	arachidonic acid secretion	NMUR2	IDA		Human	PMID:10887190
Biological Process	GO:0006816	calcium ion transport	NMUR2	IDA		Human	PMID:10899166
Biological Process	GO:0007417	central nervous system development	NMUR2	IEP		Human	PMID:10899166
Biological Process	GO:0048512	circadian behavior	nmur3	IGI	ZFIN:ZDB-GENO-160426-2	Zfish	PMID:26889812
Biological Process	GO:0007625	grooming behavior	Nmur2	IMP	MGI:MGI:3701426	Mouse	PMID:17030627
Biological Process	GO:0048016	inositol phosphate-mediated signaling	NMUR2	IDA		Human	PMID:10899166
Biological Process	GO:0007218	neuropeptide signaling pathway	NMUR2	IDA		Human	PMID:10894543
Biological Process	GO:0007218	neuropeptide signaling pathway	Nmur2	IDA		Mouse	PMID:15635449
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	NMUR2	IDA		Human	PMID:10899166
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	NMUR2	IDA		Human	PMID:10899166
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	Nmur2	IMP	MGI:MGI:3701426	Mouse	PMID:17030627
Biological Process	GO:0051930	regulation of sensory perception of pain	Nmur2	IDA		Rat	PMID:12890516|RGD:1642124
Biological Process	GO:0048265	response to pain	Nmur2	IMP	MGI:MGI:3701426	Mouse	PMID:17030627

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern