Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFAM1
  • Mouse genes Nfam1
  • Rat genes Nfam1
  • Zfish genes si:ch211-243a20.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfam1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NFAM1	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFAM1	IPI	UniProtKB:Q969L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFAM1	IPI	UniProtKB:Q9H165-2	Human	PMID:32296183
Molecular Function	GO:0004888	transmembrane signaling receptor activity	NFAM1	IDA		Human	PMID:12615919
Cellular Component	GO:0009986	cell surface	Nfam1	IDA		Mouse	PMID:15143214
Cellular Component	GO:0016020	membrane	NFAM1	IDA		Human	PMID:12615919
Cellular Component	GO:0045121	membrane raft	Nfam1	IDA		Mouse	PMID:15143214
Biological Process	GO:0030183	B cell differentiation	Nfam1	IMP		Mouse	MGI:MGI:3044463|PMID:15143214
Biological Process	GO:0050853	B cell receptor signaling pathway	Nfam1	IDA		Mouse	PMID:15143214
Biological Process	GO:0035556	intracellular signal transduction	NFAM1	IDA		Human	PMID:12615919
Biological Process	GO:0050861	positive regulation of B cell receptor signaling pathway	Nfam1	IMP		Mouse	MGI:MGI:3044463|PMID:15143214
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	NFAM1	IDA		Human	PMID:12615919
Biological Process	GO:0045577	regulation of B cell differentiation	Nfam1	IDA		Mouse	PMID:15143214
Biological Process	GO:0007165	signal transduction	NFAM1	IDA		Human	PMID:12615919

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern