Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEUROG3
  • Mouse genes Neurog3
  • Rat genes Neurog3
  • Zfish genes neurog3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neurog3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Neurog3	IDA		Mouse	MGI:MGI:3619850|PMID:16511571
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Neurog3	IDA		Mouse	MGI:MGI:4420345|PMID:19759004
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Neurog3	IDA		Rat	PMID:9130143|RGD:633362
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Neurog3	IDA		Mouse	PMID:16511571
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	NEUROG3	IDA		Human	PMID:14576336
Molecular Function	GO:0003690	double-stranded DNA binding	Neurog3	IDA		Rat	PMID:9130143|RGD:633362
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q99081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q99081-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q99081-3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q99081	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NEUROG3	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Neurog3	IPI	UniProtKB:Q99NA2	Mouse	MGI:MGI:3798332|PMID:18560595
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NEUROG3	IDA		Human	PMID:14576336
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Neurog3	IDA		Mouse	MGI:MGI:3619850|PMID:16511571
Cellular Component	GO:0005737	cytoplasm	Neurog3	IDA		Rat	PMID:16514419|RGD:1641813
Cellular Component	GO:0005622	intracellular anatomical structure	Neurog3	IDA		Mouse	PMID:10868931
Cellular Component	GO:0005622	intracellular anatomical structure	Neurog3	IDA		Mouse	PMID:15793245
Cellular Component	GO:0005634	nucleus	NEUROG3	IDA		Human	PMID:20807725
Cellular Component	GO:0005634	nucleus	Neurog3	IDA		Mouse	PMID:17928203
Cellular Component	GO:0005634	nucleus	Neurog3	IDA		Mouse	PMID:12921743
Cellular Component	GO:0005634	nucleus	Neurog3	IDA		Rat	PMID:16514419|RGD:1641813
Biological Process	GO:0030855	epithelial cell differentiation	Neurog3	IMP	MGI:MGI:2651394	Mouse	PMID:12080087
Biological Process	GO:0030900	forebrain development	Neurog3	IEP		Rat	PMID:9130143|RGD:633362
Biological Process	GO:0030902	hindbrain development	Neurog3	IEP		Rat	PMID:9130143|RGD:633362
Biological Process	GO:0007275	multicellular organism development	Neurog3	IMP	MGI:MGI:2651394	Mouse	PMID:12080087
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NEUROG3	IDA		Human	PMID:14576336
Biological Process	GO:0045597	positive regulation of cell differentiation	Neurog3	IEP		Rat	PMID:16514419|RGD:1641813
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Neurog3	IDA		Mouse	MGI:MGI:4420345|PMID:19759004
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurog3	IMP		Rat	PMID:9238023|RGD:1642078
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NEUROG3	IDA		Human	PMID:16511571
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog3	IDA		Mouse	PMID:16511571
Biological Process	GO:0048814	regulation of dendrite morphogenesis	Neurog3	IGI	MGI:MGI:101815	Mouse	PMID:21818269
Biological Process	GO:0006355	regulation of DNA-templated transcription	Neurog3	IDA		Rat	PMID:9130143|RGD:633362
Biological Process	GO:0021510	spinal cord development	Neurog3	IEP		Rat	PMID:9130143|RGD:633362
Biological Process	GO:0060290	transdifferentiation	Neurog3	IDA		Mouse	MGI:MGI:3619850|PMID:16511571

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern