Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NENF
  • Mouse genes Nenf
  • Rat genes Nenf
  • Zfish genes nenf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nenf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008083	growth factor activity	Nenf	IDA		Mouse	PMID:15605373
Molecular Function	GO:0005515	protein binding	NENF	IPI	UniProtKB:Q99497|UniProtKB:Q9BXM7	Human	PMID:31536960
Molecular Function	GO:0005515	protein binding	Nenf	IPI	UniProtKB:Q99LX0|UniProtKB:Q99MQ3	Mouse	MGI:MGI:6383486|PMID:31536960
Molecular Function	GO:0005515	protein binding	Nenf	IPI	UniProtKB:B5DFG1|UniProtKB:O88767	Rat	PMID:31536960|RGD:15090841
Cellular Component	GO:0005783	endoplasmic reticulum	NENF	IDA		Human	PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Nenf	IDA		Mouse	MGI:MGI:6383486|PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Nenf	IDA		Rat	PMID:31536960|RGD:15090841
Cellular Component	GO:0005615	extracellular space	NENF	IDA		Human	PMID:31536960
Cellular Component	GO:0005615	extracellular space	Nenf	IDA		Mouse	PMID:15605373
Cellular Component	GO:0005739	mitochondrion	NENF	IDA		Human	PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Nenf	IDA		Mouse	MGI:MGI:6383486|PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Nenf	IDA		Rat	PMID:31536960|RGD:15090841
Biological Process	GO:0000165	MAPK cascade	Nenf	IDA		Mouse	PMID:15605373
Biological Process	GO:0032099	negative regulation of appetite	Nenf	IDA		Mouse	MGI:MGI:5496967|PMID:23576617
Biological Process	GO:1901215	negative regulation of neuron death	NENF	IMP		Human	PMID:31536960
Biological Process	GO:0043410	positive regulation of MAPK cascade	Nenf	IDA		Mouse	PMID:15605373

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern