Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NELL1
  • Mouse genes Nell1
  • Rat genes Nell1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nell1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Nell1	IDA		Rat	PMID:10548494|RGD:633407
Molecular Function	GO:0042802	identical protein binding	Nell1	IPI	RGD:620998	Rat	PMID:10548494|RGD:633407
Molecular Function	GO:0005515	protein binding	NELL1	IPI	UniProtKB:Q6UW56	Human	PMID:21723284
Molecular Function	GO:0005515	protein binding	NELL1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005080	protein kinase C binding	Nell1	IDA		Rat	PMID:10600492|RGD:633406
Cellular Component	GO:0005737	cytoplasm	NELL1	IDA		Human	PMID:21723284
Cellular Component	GO:0005737	cytoplasm	Nell1	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0005615	extracellular space	Nell1	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0005635	nuclear envelope	NELL1	IDA		Human	PMID:21723284
Cellular Component	GO:0048471	perinuclear region of cytoplasm	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0033689	negative regulation of osteoblast proliferation	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0042177	negative regulation of protein catabolic process	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0043065	positive regulation of apoptotic process	Nell1	IDA		Rat	PMID:14672347|RGD:1304274
Biological Process	GO:0030501	positive regulation of bone mineralization	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0045778	positive regulation of ossification	Nell1	IMP		Rat	PMID:19493425|RGD:2314454
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0010468	regulation of gene expression	NELL1	IDA		Human	PMID:21723284
Biological Process	GO:0045667	regulation of osteoblast differentiation	Nell1	IMP		Rat	PMID:12235118|RGD:633405

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern