Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NBN
  • Mouse genes Nbn
  • Rat genes Nbn
  • Zfish genes nbn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nbn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	Nbn	IDA		Mouse	PMID:11934988
Molecular Function	GO:0140297	DNA-binding transcription factor binding	NBN	IPI	UniProtKB:Q01094	Human	PMID:11486038
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:12419185
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:12419185
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P23497	Human	PMID:12470659
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:12607005
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P15336	Human	PMID:15916964
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:16377563
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:17612497
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q96EB6	Human	PMID:17612497
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:18001824
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:18001824
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:18001825
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:18583988
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:18583988
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:18678890
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q9BXW9	Human	PMID:19609304
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q68E01	Human	PMID:19683501
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q99708	Human	PMID:19759395
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:19804756
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:20224574
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q09472	Human	PMID:21108945
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:22078559
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:22157895
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P16104	Human	PMID:22565321
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q99708	Human	PMID:22565321
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:O75943	Human	PMID:24534091
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q61687	Human	PMID:24651726
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q13428	Human	PMID:25064736
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:25064736
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q99708	Human	PMID:25558984
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q13315	Human	PMID:25895060
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q99986	Human	PMID:26869104
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q6NTE8	Human	PMID:27568553
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:Q14676	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	NBN	IPI	UniProtKB:P49959	Human	PMID:9590181
Molecular Function	GO:0005515	protein binding	Nbn	IPI	UniProtKB:Q61216	Mouse	MGI:MGI:3770108|PMID:17429352
Molecular Function	GO:0005515	protein binding	Nbn	IPI	UniProtKB:Q61216	Mouse	MGI:MGI:3839734|PMID:18854157
Molecular Function	GO:0005515	protein binding	Nbn	IPI	UniProtKB:Q8BHZ5	Mouse	MGI:MGI:6202149|PMID:30017584
Cellular Component	GO:0070533	BRCA1-C complex	NBN	IPI		Human	PMID:16391231
Cellular Component	GO:0000781	chromosome, telomeric region	NBN	IDA		Human	PMID:10888888
Cellular Component	GO:0000781	chromosome, telomeric region	NBN	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	Nbn	IDA		Mouse	MGI:MGI:5705215|PMID:23444137
Cellular Component	GO:0000781	chromosome, telomeric region	Nbn	IDA		Mouse	MGI:MGI:5705229|PMID:10811102
Cellular Component	GO:0005794	Golgi apparatus	NBN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030870	Mre11 complex	NBN	IPI		Human	PMID:31147924
Cellular Component	GO:0030870	Mre11 complex	NBN	IDA		Human	PMID:10888888
Cellular Component	GO:0030870	Mre11 complex	NBN	IDA		Human	PMID:19151086
Cellular Component	GO:0030870	Mre11 complex	NBN	IDA		Human	PMID:9590181
Cellular Component	GO:0042405	nuclear inclusion body	NBN	IDA		Human	PMID:12447371
Cellular Component	GO:0005730	nucleolus	NBN	IDA		Human	PMID:10888888
Cellular Component	GO:0005654	nucleoplasm	NBN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NBN	IDA		Human	PMID:10888888
Cellular Component	GO:0005634	nucleus	Nbn	IDA		Mouse	PMID:11555636
Cellular Component	GO:0016605	PML body	NBN	IDA		Human	PMID:10811102
Cellular Component	GO:0016605	PML body	NBN	IDA		Human	PMID:12470659
Cellular Component	GO:0016605	PML body	Nbn	IDA		Mouse	MGI:MGI:5705215|PMID:23444137
Cellular Component	GO:0005657	replication fork	Nbn	IDA		Mouse	PMID:11934988
Cellular Component	GO:0035861	site of double-strand break	NBN	IDA		Human	PMID:15916964
Biological Process	GO:0001832	blastocyst growth	Nbn	IMP		Mouse	MGI:MGI:2680772|PMID:14612522
Biological Process	GO:0000077	DNA damage checkpoint signaling	NBN	IDA		Human	PMID:12529385
Biological Process	GO:0032508	DNA duplex unwinding	NBN	IMP		Human	PMID:15790808
Biological Process	GO:0006302	double-strand break repair	NBN	IDA		Human	PMID:9590181
Biological Process	GO:0001701	in utero embryonic development	Nbn	IMP		Mouse	MGI:MGI:2680772|PMID:14612522
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Nbn	IMP	MGI:MGI:3027036	Mouse	PMID:18614044
Biological Process	GO:0045190	isotype switching	Nbn	IDA		Mouse	MGI:MGI:3529405|PMID:15668383
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	NBN	IDA		Human	PMID:11438675
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	Nbn	IMP	MGI:MGI:2183796	Mouse	PMID:18614044
Biological Process	GO:0045665	negative regulation of neuron differentiation	Nbn	IMP		Rat	PMID:17442057|RGD:2298997
Biological Process	GO:1904354	negative regulation of telomere capping	NBN	IMP		Human	PMID:17694070
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Nbn	IMP		Rat	PMID:22850678|RGD:8693392
Biological Process	GO:0007405	neuroblast proliferation	Nbn	IMP	MGI:MGI:3578646	Mouse	PMID:15821748
Biological Process	GO:0050885	neuromuscular process controlling balance	Nbn	IMP	MGI:MGI:3578646	Mouse	PMID:15821748
Biological Process	GO:0008284	positive regulation of cell population proliferation	Nbn	IMP		Rat	PMID:17442057|RGD:2298997
Biological Process	GO:0033674	positive regulation of kinase activity	NBN	IDA		Human	PMID:15790808
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	NBN	IDA		Human	PMID:15790808
Biological Process	GO:0032206	positive regulation of telomere maintenance	NBN	IMP		Human	PMID:16374507
Biological Process	GO:0048145	regulation of fibroblast proliferation	Nbn	IDA		Rat	PMID:12637527|RGD:8554316
Biological Process	GO:0009410	response to xenobiotic stimulus	Nbn	IEP		Rat	PMID:18253720|RGD:2298996
Biological Process	GO:0090656	t-circle formation	NBN	IMP		Human	PMID:27918544
Biological Process	GO:0000723	telomere maintenance	NBN	IMP		Human	PMID:11448772
Biological Process	GO:0090737	telomere maintenance via telomere trimming	NBN	IGI	UniProtKB:O43542	Human	PMID:27918544
Biological Process	GO:0031860	telomeric 3' overhang formation	NBN	IMP		Human	PMID:16374507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern