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Gene Ontology Browser
Term Detail
GO term:DNA duplex unwinding
Synonym: DNA unwinding
Synonym: duplex DNA melting
GO id:GO:0032508
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
CommentsNote that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-aDNA metabolic process
                                                is-aDNA conformation change
                                                        is-aDNA geometric change
                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                        is-aDNA unwinding involved in DNA replication +
                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                is-aDNA rewinding
                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aheterocycle metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-aDNA metabolic process
                                                is-aDNA conformation change
                                                        is-aDNA geometric change
                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                        is-aDNA unwinding involved in DNA replication +
                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                is-aDNA rewinding
                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aheterocycle metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-anitrogen compound metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-aDNA metabolic process
                                                        is-aDNA conformation change
                                                                is-aDNA geometric change
                                                                        is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                is-aDNA unwinding involved in DNA replication +
                                                                                is-anucleotide-excision repair, DNA duplex unwinding
                                                                        is-aDNA rewinding
                                                                        is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-anucleic acid metabolic process
                                                is-aDNA metabolic process
                                                        is-aDNA conformation change
                                                                is-aDNA geometric change
                                                                        is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                is-aDNA unwinding involved in DNA replication +
                                                                                is-anucleotide-excision repair, DNA duplex unwinding
                                                                        is-aDNA rewinding
                                                                        is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic cyclic compound metabolic process
                                        is-anucleobase-containing compound metabolic process
                                                is-anucleic acid metabolic process
                                                        is-aDNA metabolic process
                                                                is-aDNA conformation change
                                                                        is-aDNA geometric change
                                                                                is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                        is-aDNA unwinding involved in DNA replication +
                                                                                        is-anucleotide-excision repair, DNA duplex unwinding
                                                                                is-aDNA rewinding
                                                                                is-aG-quadruplex DNA unwinding


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-anucleobase-containing compound metabolic process
                                        is-anucleic acid metabolic process
                                                is-aDNA metabolic process
                                                        is-aDNA conformation change
                                                                is-aDNA geometric change
                                                                        is-aDNA duplex unwinding [GO:0032508] (33 genes, 36 annotations)
                                                                                is-aDNA unwinding involved in DNA replication +
                                                                                is-anucleotide-excision repair, DNA duplex unwinding
                                                                        is-aDNA rewinding
                                                                        is-aG-quadruplex DNA unwinding


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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory