Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NAXE
  • Mouse genes Naxe
  • Rat genes Naxe
  • Zfish genes naxe
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Naxe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Naxe	IPI	PR:Q8K4Z3	Mouse	PMID:18202122
Molecular Function	GO:0052856	NADHX epimerase activity	Naxe	IDA		Rat	PMID:24611804|RGD:10047272
Molecular Function	GO:0052857	NADPHX epimerase activity	Naxe	IDA		Rat	PMID:24611804|RGD:10047272
Molecular Function	GO:0005515	protein binding	NAXE	IPI	UniProtKB:P02647	Human	PMID:11991719
Molecular Function	GO:0005515	protein binding	NAXE	IPI	UniProtKB:P02652	Human	PMID:11991719
Molecular Function	GO:0005515	protein binding	NAXE	IPI	UniProtKB:P02647	Human	PMID:23719382
Molecular Function	GO:0005515	protein binding	naxe	IPI	UniProtKB:P02647	Zfish	PMID:23719382|ZFIN:ZDB-PUB-130708-22
Cellular Component	GO:0044297	cell body	Naxe	IDA		Mouse	PMID:18202122
Cellular Component	GO:0005929	cilium	Naxe	IDA		Mouse	PMID:18202122
Cellular Component	GO:0070062	extracellular exosome	NAXE	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	NAXE	IDA		Human	PMID:11991719
Cellular Component	GO:0005615	extracellular space	Naxe	IDA		Mouse	PMID:18202122
Cellular Component	GO:0005739	mitochondrion	Naxe	HDA		Mouse	PMID:18614015
Biological Process	GO:0031580	membrane raft distribution	NAXE	IMP	ZFIN:ZDB-MRPHLNO-130813-3	Human	PMID:23719382
Biological Process	GO:0016525	negative regulation of angiogenesis	NAXE	IMP	ZFIN:ZDB-MRPHLNO-130813-3	Human	PMID:23719382
Biological Process	GO:0046496	nicotinamide nucleotide metabolic process	NAXE	IMP		Human	PMID:27616477
Biological Process	GO:0010874	regulation of cholesterol efflux	NAXE	IMP	ZFIN:ZDB-MRPHLNO-130813-3	Human	PMID:23719382
Biological Process	GO:0002040	sprouting angiogenesis	NAXE	IMP	ZFIN:ZDB-MRPHLNO-130813-3	Human	PMID:23719382

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern