Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYT1
  • Mouse genes Myt1
  • Rat genes Myt1
  • Zfish genes myt1a,myt1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Myt1	IDA		Mouse	PMID:17442045
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Myt1	IDA		Mouse	MGI:MGI:3769584|PMID:17442045
Molecular Function	GO:0005515	protein binding	Myt1	IPI	UniProtKB:Q13547	Mouse	PMID:15935060
Molecular Function	GO:0005515	protein binding	Myt1	IPI	PR:Q62141-3	Mouse	PMID:15935060
Molecular Function	GO:0005515	protein binding	Myt1	IPI	PR:Q62141-2	Mouse	PMID:15935060
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Myt1	IDA		Mouse	MGI:MGI:3769584|PMID:17442045
Cellular Component	GO:0005829	cytosol	MYT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MYT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Myt1	IDA		Mouse	PMID:17928203
Cellular Component	GO:0005634	nucleus	Myt1	IDA		Mouse	PMID:9373037
Biological Process	GO:1904888	cranial skeletal system development	myt1a	IMP	ZFIN:ZDB-MRPHLNO-190328-1	Zfish	PMID:27358179
Biological Process	GO:0060539	diaphragm development	Myt1	IMP	MGI:MGI:3765054	Mouse	PMID:17928203
Biological Process	GO:0031018	endocrine pancreas development	Myt1	IMP		Mouse	PMID:17928203
Biological Process	GO:0001678	intracellular glucose homeostasis	Myt1	IMP		Mouse	PMID:17928203
Biological Process	GO:0010629	negative regulation of gene expression	Myt1	IMP		Mouse	PMID:17928203
Biological Process	GO:0003322	pancreatic A cell development	myt1b	IMP	ZFIN:ZDB-GENO-180604-3	Zfish	PMID:28327131
Biological Process	GO:0010628	positive regulation of gene expression	Myt1	IMP		Mouse	PMID:17928203
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myt1	IDA		Mouse	MGI:MGI:3769584|PMID:17442045
Biological Process	GO:0009791	post-embryonic development	Myt1	IMP	MGI:MGI:3765054	Mouse	PMID:17928203
Biological Process	GO:0032350	regulation of hormone metabolic process	Myt1	IMP	MGI:MGI:3765054	Mouse	PMID:17928203
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Myt1	IMP		Mouse	PMID:17928203

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern