Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myo5b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYO5B
- Mouse genes Myo5b
- Rat genes Myo5b
- Zfish genes myo5b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Myo5b	IMP		Rat	PMID:14766983\|RGD:13461756
Molecular Function	GO:0016887	ATP hydrolysis activity	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Myo5b	IPI	RGD:621531	Rat	PMID:16338934\|RGD:2312658
Molecular Function	GO:0005515	protein binding	MYO5B	IPI	UniProtKB:Q9UHC9	Human	PMID:19542231
Molecular Function	GO:0005515	protein binding	MYO5B	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYO5B	IPI	UniProtKB:Q12982	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYO5B	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYO5B	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Myo5b	IPI	UniProtKB:Q6T3U4	Mouse	MGI:MGI:6160379\|PMID:29880681
Molecular Function	GO:0005515	protein binding	Myo5b	IPI	UniProtKB:Q9ERG0	Mouse	MGI:MGI:6160379\|PMID:29880681
Molecular Function	GO:0005515	protein binding	Myo5b	IPI	UniProtKB:P19490	Rat	PMID:16338934\|RGD:2312658
Molecular Function	GO:0031267	small GTPase binding	MYO5B	IPI	UniProtKB:P62491	Human	PMID:17462998
Molecular Function	GO:0031267	small GTPase binding	Myo5b	IPI	RGD:620879	Rat	PMID:23770993\|RGD:11533641
Cellular Component	GO:0045179	apical cortex	MYO5B	IDA		Human	PMID:21206382
Cellular Component	GO:0005903	brush border	Myo5b	IDA		Mouse	MGI:MGI:5621262\|PMID:22114352
Cellular Component	GO:0043197	dendritic spine	Myo5b	IDA		Rat	PMID:16338934\|RGD:2312658
Cellular Component	GO:0070062	extracellular exosome	MYO5B	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098978	glutamatergic synapse	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0043005	neuron projection	Myo5b	IDA		Rat	PMID:16338934\|RGD:2312658
Cellular Component	GO:0043025	neuronal cell body	Myo5b	IDA		Rat	PMID:16338934\|RGD:2312658
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo5b	IDA		Rat	PMID:16338934\|RGD:2312658
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo5b	IDA		Rat	PMID:18701652\|RGD:2306295
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo5b	IDA		Rat	PMID:25456499\|RGD:11532775
Cellular Component	GO:0098794	postsynapse	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098944	postsynaptic recycling endosome membrane	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098944	postsynaptic recycling endosome membrane	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0032991	protein-containing complex	MYO5B	IDA		Human	PMID:17462998
Cellular Component	GO:0055037	recycling endosome	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo5b	IDA		Mouse	PMID:18984164
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo5b	IMP		Mouse	PMID:18984164
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0061564	axon development	myo5b	IMP	ZFIN:ZDB-MRPHLNO-160310-1	Zfish	PMID:23770993
Biological Process	GO:0003242	cardiac chamber ballooning	myo5b	IMP	ZFIN:ZDB-GENO-191003-3	Zfish	PMID:30801852
Biological Process	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis	myo5b	IMP	ZFIN:ZDB-GENO-191003-3	Zfish	PMID:30801852
Biological Process	GO:1905430	cellular response to glycine	Myo5b	IEP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0060997	dendritic spine morphogenesis	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0048546	digestive tract morphogenesis	myo5b	IMP	ZFIN:ZDB-GENO-170126-23	Zfish	PMID:27497746
Biological Process	GO:0032456	endocytic recycling	myo5b	IMP	ZFIN:ZDB-GENO-191003-3	Zfish	PMID:30801852
Biological Process	GO:0016197	endosomal transport	MYO5B	IMP		Human	PMID:21206382
Biological Process	GO:0098856	intestinal lipid absorption	myo5b	IMP	ZFIN:ZDB-GENO-170126-23	Zfish	PMID:27497746
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Myo5b	IDA		Mouse	PMID:18984164
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Myo5b	IMP		Mouse	PMID:18984164
Biological Process	GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0045773	positive regulation of axon extension	Myo5b	IMP		Rat	PMID:23770993\|RGD:11533641
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Myo5b	IMP		Rat	PMID:23554492\|RGD:11533644
Biological Process	GO:1903543	positive regulation of exosomal secretion	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Myo5b	IMP		Rat	PMID:19542231\|RGD:11533638
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Myo5b	IMP		Rat	PMID:24508725\|RGD:11532777
Biological Process	GO:0015031	protein transport	Myo5b	IMP		Rat	PMID:17156409\|RGD:2312655
Biological Process	GO:0008361	regulation of cell size	myo5b	IMP	ZFIN:ZDB-GENO-150514-1	Zfish	PMID:25233349
Biological Process	GO:0008361	regulation of cell size	myo5b	IMP	ZFIN:ZDB-GENO-150514-2	Zfish	PMID:25233349
Biological Process	GO:0008361	regulation of cell size	myo5b	IMP	ZFIN:ZDB-MRPHLNO-141231-1	Zfish	PMID:25233349
Biological Process	GO:0008361	regulation of cell size	myo5b	IMP	ZFIN:ZDB-GENO-111017-18	Zfish	PMID:25233349
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0032880	regulation of protein localization	Myo5b	IMP		Rat	PMID:18701652\|RGD:2306295
Biological Process	GO:0043588	skin development	myo5b	IMP		Zfish	PMID:9007245
Biological Process	GO:0036466	synaptic vesicle recycling via endosome	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0036466	synaptic vesicle recycling via endosome	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0016192	vesicle-mediated transport	MYO5B	IMP		Human	PMID:17462998
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Myo5b	IDA		Rat	PMID:18984164\|RGD:11533643
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Myo5b	IMP		Rat	PMID:18984164\|RGD:11533643

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.