Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMP11
  • Mouse genes Mmp11
  • Rat genes Mmp11
  • Zfish genes mmp11a,mmp11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmp11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008237	metallopeptidase activity	Mmp11	IDA		Mouse	PMID:18622425
Molecular Function	GO:0008237	metallopeptidase activity	mmp11a	IDA		Zfish	PMID:31816958
Molecular Function	GO:0005515	protein binding	mmp11b	IPI	ZFIN:ZDB-GENE-100603-1	Zfish	PMID:31816958
Molecular Function	GO:0005515	protein binding	mmp11b	IPI	ZFIN:ZDB-GENE-070824-1	Zfish	PMID:31816958
Cellular Component	GO:0031012	extracellular matrix	MMP11	IDA		Human	PMID:18622425
Biological Process	GO:0071711	basement membrane organization	Mmp11	IMP	MGI:MGI:2387934	Mouse	PMID:18622425
Biological Process	GO:0030574	collagen catabolic process	Mmp11	IDA		Mouse	PMID:18622425
Biological Process	GO:0030199	collagen fibril organization	Mmp11	IMP	MGI:MGI:2387934	Mouse	PMID:18622425
Biological Process	GO:0030198	extracellular matrix organization	Mmp11	IMP	MGI:MGI:2387934	Mouse	PMID:18622425
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Mmp11	IDA		Mouse	PMID:18622425

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern