Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MLLT3
  • Mouse genes Mllt3
  • Rat genes Mllt3
  • Zfish genes mllt3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mllt3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	MLLT3	IDA		Human	PMID:25417107
Molecular Function	GO:0003682	chromatin binding	MLLT3	IDA		Human	PMID:27105114
Molecular Function	GO:0042393	histone binding	MLLT3	IDA		Human	PMID:27105114
Molecular Function	GO:0042393	histone binding	MLLT3	IDA		Human	PMID:27545619
Molecular Function	GO:0070577	lysine-acetylated histone binding	MLLT3	IDA		Human	PMID:25417107
Molecular Function	GO:0140030	modification-dependent protein binding	MLLT3	IDA		Human	PMID:27105114
Molecular Function	GO:0140030	modification-dependent protein binding	MLLT3	IDA		Human	PMID:27545619
Molecular Function	GO:0060090	molecular adaptor activity	MLLT3	EXP		Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q92624	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8TEK3	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q9UHB7	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8TEK3	Human	PMID:20203130
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:P51825	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q9UHB7	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q9NXW9	Human	PMID:23145062
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:P51825	Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q6W2J9-1	Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8TEK3	Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q9HC52	Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8TEK3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8IZU1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q5JXC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q5SQQ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q7Z3I7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q8IZU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MLLT3	IPI	UniProtKB:Q9NXW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mllt3	IPI	PR:Q8CGN4-1	Mouse	PMID:12776190
Molecular Function	GO:0005515	protein binding	Mllt3	IPI	PR:Q69ZU8	Mouse	PMID:19591803
Molecular Function	GO:0005515	protein binding	Mllt3	IPI	PR:Q8CGN4-2	Mouse	PMID:12776190
Cellular Component	GO:0005829	cytosol	MLLT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	MLLT3	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	MLLT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mllt3	IDA		Mouse	PMID:20427473
Cellular Component	GO:0008023	transcription elongation factor complex	MLLT3	IDA		Human	PMID:22195968
Cellular Component	GO:0008023	transcription elongation factor complex	MLLT3	IDA		Human	PMID:25417107
Cellular Component	GO:0008023	transcription elongation factor complex	MLLT3	IDA		Human	PMID:27105114
Biological Process	GO:0009952	anterior/posterior pattern specification	Mllt3	IMP	MGI:MGI:2388982	Mouse	PMID:12242306
Biological Process	GO:0010467	gene expression	Mllt3	IDA		Mouse	PMID:20427473
Biological Process	GO:0010467	gene expression	Mllt3	IMP		Mouse	PMID:20427473
Biological Process	GO:0060218	hematopoietic stem cell differentiation	MLLT3	IDA		Human	PMID:31776511
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	MLLT3	IDA		Human	PMID:19591803
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	MLLT3	IGI	UniProtKB:Q69ZU8	Human	PMID:19591803
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MLLT3	IDA		Human	PMID:25417107
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MLLT3	IDA		Human	PMID:27105114
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MLLT3	IDA		Human	PMID:31776511
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	MLLT3	IGI	UniProtKB:Q69ZU8	Human	PMID:19591803
Biological Process	GO:1902275	regulation of chromatin organization	MLLT3	IMP		Human	PMID:31776511
Biological Process	GO:2000035	regulation of stem cell division	MLLT3	IDA		Human	PMID:31776511
Biological Process	GO:0007379	segment specification	Mllt3	IMP	MGI:MGI:2388982	Mouse	PMID:12242306

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern