Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED17
  • Mouse genes Med17
  • Rat genes Med17
  • Zfish genes med17
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med17

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030374	nuclear receptor coactivator activity	MED17	IDA		Human	PMID:12218053
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	MED17	IDA		Human	PMID:10198638
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q15528	Human	PMID:12584197
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9CQI9	Human	PMID:12584197
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:O75586	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q15528	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q6P2C8	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9BUE0	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9CQI9	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9D7W5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9D8C6	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9H204	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q15528	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q6P2C8	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9BUE0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9H204	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED17	IPI	UniProtKB:Q9BUE0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Med17	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:3848741|PMID:19338389
Molecular Function	GO:0003713	transcription coactivator activity	MED17	IDA		Human	PMID:12037571
Molecular Function	GO:0003713	transcription coactivator activity	MED17	IDA		Human	PMID:12218053
Molecular Function	GO:0003712	transcription coregulator activity	MED17	IDA		Human	PMID:10198638
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med17	IDA		Rat	PMID:12149480|RGD:2304264
Cellular Component	GO:0070847	core mediator complex	MED17	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	MED17	IDA		Human	PMID:10198638
Cellular Component	GO:0016592	mediator complex	MED17	IDA		Human	PMID:12037571
Cellular Component	GO:0016592	mediator complex	MED17	IDA		Human	PMID:14638676
Cellular Component	GO:0016592	mediator complex	Med17	IDA		Mouse	PMID:15340084
Cellular Component	GO:0016020	membrane	MED17	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	MED17	IDA		Human	PMID:10235267
Cellular Component	GO:0005634	nucleus	MED17	IDA		Human	PMID:24882805
Cellular Component	GO:0005667	transcription regulator complex	MED17	IDA		Human	PMID:9989412
Cellular Component	GO:0000151	ubiquitin ligase complex	Med17	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MED17	IDA		Human	PMID:10198638
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MED17	IDA		Human	PMID:12037571
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	MED17	IDA		Human	PMID:12218053
Biological Process	GO:0016567	protein ubiquitination	Med17	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	MED17	IDA		Human	PMID:9989412
Biological Process	GO:0035019	somatic stem cell population maintenance	Med17	IMP		Mouse	PMID:20720539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern